ATS 2024 Final Program

Click on the session title to view the speakers

100

SUNDAY • MAYs 19

BASIC BASIC SCIENCE CORE

CLINICAL CRITICAL CARE TRACK

A85 FROM MECHANISM TO PREDICTION: APPLICATION OF METABOLOMICS ACROSS THE PULMONARY/CRITICAL CARE SPECTRUM 2:15 p.m. - 3:45 p.m. Marriott Marquis San Diego Marina Grand Ballroom 5-6 (Lobby Level, North Tower) Target Audience Objectives At the conclusion of this session, the participant will be able to: • Learn cutting-edge approaches in the study of metabolism. • Appreciate the breadth of impact of metabolism across multiple different pulmonary and critical illnesses. • Have new translational strategies to characterize disease mechanisms and high risk patient populations. Impaired metabolism is implicated in numerous disease states. Advanced technologies for mitochondrial and metabolomic assessment are increasingly applied to pulmonary and critical care diseases, allowing for enhanced characterization of disease mechanisms as well as clinical prognostication. Often "omics" feel inaccessible to clinicians and clinical researchers due to the vast volume of data, and can be difficult to apply to clinically meaningful outcomes for basic scientists. The goal of this session is to allow all audience members to see how these state-of-the-art techniques can be applied across disease states, informing disease mechanisms as well as enhancing prognostication across various pulmonary and critical care diseases. 2:15 Translational Metabolomics to Define Mechanisms in Sepsis 2:45 Spatial Assessment of Metabolism in the Lung 3:05 Application of Polymetabolite Risk Scores to Predict Outcomes in Pulmonary Vascular Disease 3:25 Using Metabolomics to Connect Genetic and Environmental Factors to Phenotype in Asthma

A86 BEYOND THE BUNDLE: SEPSIS CARE BEFORE ARRIVAL AND AFTER SURVIVAL Assemblies on Critical Care; Behavioral and Health

Services Research 2:15 p.m. - 3:45 p.m.

Marriott Marquis San Diego Marina Grand Ballroom 2-4 (Lobby Level, North Tower)

Target Audience Clinicians, researchers, trainees, and other providers, including nurses, social workers, and physical therapists, who care for patients with sepsis across the course of their illness- from before hospital arrival through recovery. Objectives At the conclusion of this session, the participant will be able to: • identify opportunities for performance improvement at two key understudied time points in sepsis: before hospital arrival and after survival • describe new research findings about pre-hospital sepsis management, including sepsis prevention and pre-hospital interventions • improve the recovery and quality of life of sepsis survivors by applying evidence-based tools to de-escalate invasive care and recognize and treat post-sepsis syndrome Despite improvement over the past few decades, sepsis remains a major cause of morbidity and mortality worldwide. Sepsis research and quality improvement initiatives have traditionally focused on recognition and prompt treatment upon arrival to the hospital. The pre-hospital and recovery periods are also important, yet understudied, time points for interventions. Specifically, this session will highlight opportunities for improving sepsis care before arrival to the hospital and after survival, both in the hospital and post-discharge, leveraging novel technologies and system-based and global interventions. 2:15 Sepsis: A Patient’s Journey 2:20 Stopping Sepsis Before It Starts: Addressing the Global Burden of Sepsis through Prevention 2:32 Moving Care Upstream: Pre-Hospital Sepsis Trajectories and Interventions 2:44 Your Patient Turned the Corner, Now What?

ATS 2024 Conference Program • San Diego, CA