ATS 2024 Final Program

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114

SUNDAY • MAYs 19

611 Effects of Electronic Cigarettes on Airway Epithelium: A Novel Exposure System and In-Vitro Model 612 Cigarette Smoke-induced Ion Channel and Mucociliary Dysfunction in COPD Airway Epithelial Cells In Vitro: Rescue by Nesolicaftor/Telmisartan 613 Characterization of Transient Mucosal Immunity Driven Terminal Bronchioles Thickening in Early Emphysematous Lung 614 Sex-dependent Impact of E-cigarette Aerosol Exposure on the Murine Lung 615 Transcriptomic Analysis Reveals Distinct Effect of Cigarette Smoke on Lung and Systemic Macrophage Populations 616 Effects of Heated Tobacco Product IQOS Exposure on Ceramide Levels and Apoptosis in Lungs 617 GZMK-expressing Immune Cells in Chronic Obstructive Pulmonary Disease 618 Plasma Proteomics Reveals Biological Pathways Associated With Probable Cognitive Impairment in the COPDGene Cohort 619 Multi-omic Studies of Lower Airway Epithelium in Spiromics Reveals COPD-associated Methylation Sites and Co-methylation Networks Enriched for Lung Function GWAS Loci and Linked to Microbiota 620 Sex-specific Differences in COPD Presentation Are Associated With Sphingolipids Metabolism 621 Involvement of Heat Shock Protein HSP70 and Ceramide Generator nSmase2 in IL-33 Driven Airway Disease 622 miRNA Network Modeling Identifies a Potential Role for PAX5 in COPD 623 Lipid-signaling as a Potential New Therapeutic Target in Chronic Obstructive Pulmonary Disease 624 Mitochondrial Cytochrome C Oxidase Subunit 4

BASIC • CLINICAL • TRANSLATIONAL RAPID POSTER DISCUSSION SESSION

A109 I JUST CAN’T GET ENOUGH:

DEFECTS IN VENTILATION AND GAS EXCHANGE Marriott Marquis San Diego Marina Pacific Ballroom 15-17 (Ground Floor, North Tower) 3:00-4:15 101 Pulmonary Mechanics Before Discharge Among Infants With and Without Lung Disease 102 Association Between Body Mass Index and Dual Energy Computed Tomographic Assessment of Ventilation and Perfusion (V/Q) in the Community: The Multi-Ethnic Study of Atherosclerosis Lung Study 103 Characterization of Pulmonary and Chest Wall Mechanics in Mechanically Ventilated Patients With Hypoxemic Respiratory Failure Across Racial and Ethnic Groups 104 Nocturnal Oxygen Saturation and Cognitive Outcomes in Individuals Permanently Residing at High Altitude 105 Association of P50 With Physiologic Variables and Outcomes in Critically Ill Patients 106 Pulmonary Gas-exchange Abnormalities Prior to Hematopoietic Stem-cell Transplantation Detected With Xenon MRI: Preliminary Results From the Transpire Study 107 Using AI-Techniques to Develop First Software for Continuous Assessment of Dyspnea and Ventilation During Incremental Cardiopulmonary Exercise Testing (DyVe-X) 108 A Quantitative Computed Tomography Assessment of Multi-frequency Ventilation in a Porcine Model of Acute Respiratory Distress Syndrome 109 Experimentally Induced Mild Flow Limited Dyssynchrony Protectsthe Injured Lung From Ventilator-Induced Lung Injury 110 Prone Positioning May Reduce Pendelluft in Patients With Moderate to Severe Acute Respiratory Distress Syndrome: A Physiological Study 2:15 p.m. - 4:15 p.m. Viewing/Discussion Abstract Summaries 2:15-3:00

Isoform 2 Promotes Murine Smoke-induced Pulmonary Inflammation and Emphysema - Therapeutic Potential of ROS Inhibition

ATS 2024 Conference Program • San Diego, CA