ATS 2024 Final Program

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133

MONDAY • MAY 20

306 Feasibility of Home-based Pulmonary Rehabilitation With Remote Monitoring in Pulmonary Arterial Hypertension 307 Enhancing Rehabilitation Programs for Complex Chronic Obstructive Pulmonary Disease (COPD) Patients: Insights From Patients and Providers 308 Characterizing Respiratory Symptoms, Physical Activity Levels, and Daily Function in Lung Transplant Candidates Managed by Palliative Care: A Mixed Methods Study 309 A New Lens for Quality of Life Measurements: Novel Application of the FACIT-pal Score 310 Characteristics of Virtual Pulmonary Rehabilitation Programs in the US: Results From a National Electronic Survey B28 LUNGS THORUGH TIME: EXPLORING LUNG AGING 9:15 a.m. - 11:15 a.m. San Diego Convention Center Room 33A-C (Upper Level) Poster Viewing 9:15-10:00 Discussion 10:00-11:15 901 Neonatal Hyperoxia Exposure Derails the Normal Development and the Physiological Ageing of the Lung 902 Association of Age Acceleration With COPD and Idiopathic Pulmonary Fibrosis in Lung and Blood Samples From the Lung Tissue Research Consortium: A Sex-Based Lens 903 A Single-cell Atlas of Human Lung Aging Reveals Cell-type Specific Signatures 904 FENDRR LNCRNA Knockout Leads to Age-associated Senescence Signature in Mouse Lung Endothelial Cells 905 Early-life Multiple Hit Model of Maternal Obesity and Cigarette Smoke Exposure Favors Early Chronic Obstructive Pulmonary Disease (COPD) Through Activation of Premature Lung Aging Processes in AT2 BASIC • TRANSLATIONAL POSTER DISCUSSION SESSION

906 Aging-related Accumulation of Truncated Oxidized Phospholipids Augments Infectious Lung Injury and Endothelial Dysfunction Via CD36-dependent Mechanism 907 Accelerated DNA Aging in Familial Pulmonary Fibrosis 908 The Role of Regulator of Telomere Elongation 1 (RTEL1) in Lung Ageing and Fibrosis 909 Chromatin Changes in the Aging Lung Determine Progenitor Cell Activity 910 Muc5b Overexpression and Aging Results in Lung Fibrosis in Mice 911 CRIPTO1 Is a New Senescence-associated Secreted Protein That Drives Fibroblast Activation During Senescence-induced Pulmonary Fibrosis 912 Extrinsic Stimuli Determine the Senescent Phenotype of Primary Human Lung Fibroblasts and Impair Stem Cell Potential of the Distal Epithelium 914 Fibroblast NF- k B Activation Drives the Accumulation of Age-associated T Cells (Taa) in the Lung 915 Lung-targeting Nox4 Inhibitors as a Novel Strategy for Age-dependent Severe ARDS 916 Decreased Glycolysis Reduces Senescence in Cultured Lung Macrophages Exposed to Hyperoxia and Increased Glycolysis Is Associated With Hyperoxia-Induced Lung Senescence In Vivo 917 Caveolin-1-Derived Peptide Improves Telomere Function by Targeting P53-fibrinolytic Pathway During Chronic Lung Injuries 918 Circulating Extracellular Vesicles Isolated From Young Mice Protect Aged Endothelial Cells and Exert Anti-fibrotic Effects in Aged Mice With Persistent Lung Fibrosis 919 Changes in Lung Extracellular Matrix Stiffness Caused by Aging: Dependence on Whether Measured at Functional or Residual Volumes 920 Endothelial Cell Senescence in Pulmonary Arterial Hypertension: A Two-edge Sword? 913 Nampt Mediates Apoptosis-resistance of Myofibroblasts That Contributes to Age-dependent Persistent Lung Fibrosis

ATS 2024 Conference Program • San Diego, CA