ATS 2024 Final Program

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135

MONDAY • MAY 20

722 Ubiquitin Ligase HRD1 Facilitates Degradation of the Type I Collagen in Idiopathic Pulmonary Fibrosis 723 Apoptotic Resistance in Collagen1a1-expressing Fibroblasts Drives Silica-induced Pulmonary Fibrosis 724 Single Cell Transcriptomic Profiling Resolves a Therapeutic Gap in Idiopathic Pulmonary Fibrosis 725 Small-molecule Targeting of Epac1 in Idiopathic Pulmonary Fibrosis

808 Osteoprotegerin, Fibulin-1 and Latent TGFß Binding Protein 1 Form a Regulatory Complex in Lung Fibrosis 809 Lactate and Epithelial Mesenchymal Transition (EMT)- Mediated Changes in Cellular Properties by Enhanced Stiffness of an Extracellular Matrix 810 Transcriptomic Heterogeneity of the Distal Epithelium in IPF Lung: Rethinking the Order of Events 811 Severity and Extent of Pulmonary Fibrosis on CT in Idiopathic Pulmonary Fibrosis Patients Correlates With Lung Function and Quantitative CT Features 812 Association of Diaphragmatic Motion Evaluated by Dynamic Digital Radiography and Disease Progression in Patients With Idiopathic Pulmonary Fibrosis 813 Comparative Analysis of Bleomycin and Adenovirus TGFß1-induced Pulmonary Fibrosis in Preclinical Mouse Models 814 Quantification of Normal Tissue Mass From Computed Tomography in Systemic Sclerosis-associated Interstitial Lung Disease 815 A Mechanotransduction-motivated Agent-based Model of Lung Parenchymal Self-healing and Fibrosis on a Spring Network 816 Evaluating Radiomic-derived Features Across Different Image Convolution Kernels for Predicting IPF Patient Survival 817 Exploring Deep Learning Models for the Prediction of FVC Decline in IPF Patients 818 Safety, Effectiveness, and Usefulness of Higher-dose Tablets of Generic Pirfenidone in Patients With IPF: A Nationwide Observational Study in South Korea 819 Persistent Airway Remodeling in Ferrets Exposed to a Single Dose of Bleomycin 820 BRD4 Is a Novel Regulator of Pleural Mesothelial to Mesenchymal Transition 821 Transmission Electron Microscopy of Transbronchial Lung Cryobiopsy Samples in Fibrotic Interstitial Lung Diseases - Feasibility and Implications of Ultrastructural Vessel Abnormalities

BASIC • CLINICAL • TRANSLATIONAL POSTER DISCUSSION SESSION

B30 SCARRED FOR LIFE:

TRANSLATIONAL RESEARCH IN INTERSTITIAL ABNORMALITIES AND LUNG FIBROSIS

9:15 a.m. - 11:15 a.m.

San Diego Convention Center Room 31A-C (Upper Level)

Poster Viewing

9:15-10:00

Discussion 10:00-11:15 801 Fresh Perspectives on Lung Morphometry and Pulmonary Drug Delivery: AI-powered 3D Imaging in Healthy and Fibrotic Murine Lungs 802 Fibrosis in Precision Cut Lung Slices From TGF-ß1 Overexpressing Mice 803 Interleukin-1a Downregulates Transforming Growth Factor-ß1 or ß2-induced Remodeling Gene Expression in Healthy Lung Fibroblasts 804 Diet-induced Obesity Results in Severe Lung Fibrosis That Is Improved by Alk5i Treatment in a Bleomycin Induced Pulmonary Fibrosis Mouse Model 805 Deciphering the Clinical Efficacy Mechanisms of Buloxibutid in Idiopathic Pulmonary Fibrosis 806 The Role of M2-like Macrophages and Their Aggregation in the Formation of Honeycomb Cysts Expressing MUC5B in Idiopathic Pulmonary Fibrosis 807 Global Proteomic Profiling the Mechanism of Action of the Casein Kinase 1 Delta (CK1d) Inhibitor PF670462 in Modulating TGF-ß-induced Fibrogenesis

ATS 2024 Conference Program • San Diego, CA