ATS 2024 Final Program

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175

MONDAY • MAY 20

P675 Differential Genes Expression and Distinct Signaling Pathways Between Slow Twitch and Fast Twitch Muscles on Inflammatory Response in Cigarette Smoke-exposed Rat Model P676 Disruption of P53/FOXO4 Interactions in Senescent Lung Cells Results in Senolysis

P658 Vaping, but Not Smoking, Causes an Increase in Orai1-dependent Ca 2+ Signaling P659 Murine Toxicology Study of Repeat-Dose Inhaled KB408, an HSV-1-Based Vector for the Treatment of Alpha-1 Antitrypsin Deficiency P660 Puma Mediates Cigarette Smoking Induced Cell Death in the Pathogenesis of Chronic Obstructive Pulmonary Disease P661 CYP1B1 Promotes Lipid-laden Macrophage Formation Induced by Reactive Oxidative Species P662 Smoker and Nonsmoker Lungs: Single Cell RNA-sequencing P663 Vascular Endothelial Growth Factor Receptor 1 Tyrosine Kinase Signaling Iinduces Elastase Induced Pulmonary Emphysema P664 Ethanol Alters E-liquid Physicochemical Properties, Toxicity, and Nicotine Deposition P665 Associations of Metals and Gene Expression in Peripheral Blood Mononuclear Cells of Chronic Obstructive Pulmonary Disease P666 Inhaled Live Biotherapeutic Targeting Neutrophilic Inflammation Is Well Tolerated in Healthy and COPD Animal Models P667 Comparative Effects of Chronic Exposure to Heated Tobacco Products and Combustible Cigarettes in an Interstitial Lung Disease Animal Model P668 Evaluating the Cardiopulmonary Effects of a Chronic E-cigarette Exposure in a Hyperlipidemic Mouse Model P669 Aging and Metabolic Changes in COPD Patients P670 Cellular Injury Repair in the Distal Lung Following Exposure to E-cigarette Vape (EV) P671 Human Small Airway Model of COPD to Investigate Disease Mechanisms and Test Preventive Immunotherapy P672 Exploring the Therapeutic Potential of Fibroblast Growth Factor 10 Treatment in Elastase-induced Pulmonary Hypertension and Emphysema P673 The Role of CEACAM6/HO-1 Axis in a Mouse Model of Cigarette Smoke-induced Lung Injury P674 Prothymosin a Downregulates Antiaging-related Deacetylase Sirt1 in COPD

BASIC • TRANSLATIONAL THEMATIC POSTER SESSION

B71 ASTHMA PATHOGENESIS: MORE THAN MEETS THE EYE 9:15 a.m. - 4:15 p.m. Viewing: Posters will be on display for entire session Discussion: 11:30-12:30 Discussionwith facilitators, authors, andattendees 12:30-1:15 Authorswill beby their posters for individual discussionwithattendees P291 Mechanisms of Nasal Epithelial Cell Permeability in Eosinophilic Severe Asthma: Effect of Anti-IL5R Therapy P292 UnBlender: Untangling Respiratory Bulk Transcriptomics in the Lung and Nose Through Custom and Reliable Cell Type Deconvolution P293 Metabolic Characterisation of Cannabis Use Demonstrates Detrimental Impact on Future Health Outcomes in Asthmatics P294 T2/IL-13-induced Autophagy Promotes RV-A16 Infection in Human Airway Epithelial Cells P295 Evaluation of Exosomal Microrna Profiles in Induced Sputum According to Inflammatory Phenotypes in Patients With Severe Asthma P296 Improved Annotation of Asthma Gene Variants With Cell Type Deconvolution of Nasal and Lung Expression-Quantitative Trait Loci P297 Inhaled AZD4604: Local Janus Kinase 1 Inhibition Without Systemic Activity P298 Identification of Key Genes Associated With Epithelial Barrier Dysfunction for Patients With Asthma by Comprehensive Analysis San Diego Convention Center Area C (Hall A-B2, Ground Level)

ATS 2024 Conference Program • San Diego, CA