ATS 2024 Final Program

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178

MONDAY • MAY 20

P63 Pleural Cavity Inflammation During Ventilator-induced Lung Injury Is Mediated by Purinergic Signalling P64 Decreased Circulating Eicosapentaenoic Acid Is Associated With Increased Risk of Acute Respiratory Distress Syndrome P65 Rho Kinase Inhibition Exacerbates Ventilator-Induced Lung Injury P66 Hif1a-related Transcriptomic Changes During Atelectasis With or Without Systemic Endotoxemia: An Exploratory Analysis P67 Reduction of Acute Lung Injury by Mesenchymal Stem Cell-derived Extracellular Vesicles P68 High Resolution Analysis of Chromatin Sensitivity and Transcription Factor (TF) Occupancy, in Hypoxic Endothelial Cells

P74 C3a Drives Hexokinase 2-dependent “Warburg Effect” and Mitochondrial Dysfunction in Mesenchymal Cells Derived From Lung Transplant Patients P75 Targeting C3ar Mitigates Metabolic Reprogramming and Proinflammatory Priming in Lung Ischemic Reperfusion Injury P76 Longitudinal Lower Airway Microbial Signatures of Chronic Lung Allograft Dysfunction in Lung Transplantation P77 Cellular Culprits: Unveiling the Activated Phenotypes of Immune Cells in Lung Transplant Acute Cellular Rejection Through Single-cell Analysis P78 Immune Playbook: Single-cell Analysis Reveals a Shift From Defensive Macrophage and NK to Offensive Memory and Cytotoxic T Cells in Lung Allograft Acute Cellular Rejection P79 Deciphering Long Non-coding RNA Expression Patterns in Lung Allograft Rejection With Single-cell Sequencing P80 Post-transcriptional Regulation of Autotaxin Involves RNA-binding Protein HuR and Its Intermediate Role in MNK/eIF4E Activation Within Lung-transplanted Mesenchymal Cells P81 The Association of an IPF Polygenic Risk Score With Diagnosis, Mortality and Lung Transplantation in a Hospital Biobank P82 Strengthening Pulmonary Research With Fresh Human Tissue Distributed From the Ohio State Biobank P83 Demographics of Lung Transplant Recipients Participating in Explant Tissue Collection at the University of California San Diego P84 Human Donor Lungs Supported With Human:Porcine Xenogeneic Cross Circulation Maintain Physiologic Function After Re-exposure to Human Blood, Despite Ongoing Cross-Species Immunoreactivity P85 Vitamin A and MITF Regulation in Lymphangioleimyomatosis P86 Dysregulated Complement and Autophagy in Non-resolvable-COVID-19 Patients Requiring Lung Transplantation P87 Epithelial-Derived Biomarkers in Chronic Lung Allograft Rejection

BASIC • TRANSLATIONAL THEMATIC POSTER SESSION

B74 BREATHING NEW LIFE: LUNG

TRANSPLANT PATHOGENESIS AND MECHANISMS

9:15 a.m. - 4:15 p.m.

San Diego Convention Center Area A (Hall A-B2, Ground Level)

Viewing: Posters will be on display for entire session Discussion: 11:30-12:30 Discussionwith facilitators, authors, andattendees 12:30-1:15 Authorswill beby their posters for individual discussionwithattendees P70 Early Post-transplant Genomic Storm Predict Allograft Function and Survival in Lung Transplant Recipients P71 Recipient Age Determines Lung Function and Outcomes in Mouse Models of Lung Transplantation P72 Leveraging Blood-based Transcriptomics to Detect Acute Cellular Rejection in Lung Transplant P73 TMEM27 Deficiency in Alveolar Type II Epithelial Cells Protected Against Endoplasmic Reticulum Stress Induced Ferroptosis During Lung Ischemia Reperfusion Injury

ATS 2024 Conference Program • San Diego, CA