ATS 2024 Final Program

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193

MONDAY • MAY 20

12:15 Feline Asthma: A Model Concordant with Human Eosinophilic Asthma and its Airway Microbiome 12:30 Equine Asthma: A Non-Eosinophilic Model of Human Asthma and Study of its Airway Microbiome 12:45 Human Asthma and the Microbiome: What Can We Learn from Other Species?

12:00 PVDOMICS - Metabolomics and Right Ventricular Function 12:15 Sleep Disordered Breathing-Metabolomics Work in Relation to Clinical Outcomes 12:30 RNA Sequencing Analysis, Delving into the Surprising and Unknown 12:45 Person-Specific Network Analyses CENTERS FOR DISEASE CONTROL AND PREVENTION MID-DAY SESSION MD19 OVERVIEWOF CDC’S SUPPORT, COLLABORATION, ANDRESPONSEWORK RELATED TOWILDLAND FIRES 12:00 p.m. - 1:00 p.m. Marriott Marquis San Diego Marina Grand Ballroom 11-13 (Lobby Level, North Tower) Target Audience Clinicians and public health professionals interested in population health issues relating to wildland fire. Objectives At the conclusion of this session, the participant will be able to: • better understand the public health importance and burden of wildland fire on population health. • better understand of programmatic work and partnerships at the federal level to assess and address issues associated with wildland fire. • identify areas where participants and their communities may be impacted by wildland fire and its smoke as well as actions that they can take to prepare and respond to these issues. Climate change, policies that led to unnatural accumulations of fuels, and urban expansion have resulted in a 4-fold increase in acreage burned by wildfires in the United States between 1985 and 2019. Wildland fire smoke now accounts for more than 50% of PM2.5 concentrations in many western states. The 2023 wildfires demonstrated that this is a transnational problem. This session will discuss the efforts of the Centers for Disease Control and Prevention’s (CDC) and its partner organizations to assess and address the cumulative public health impacts of wildland fire in regard to prevention, mitigation, preparedness, response, and recovery. 12:00 The Impact of Wildland Fire Smoke on Human Health

NATIONAL HEART, LUNG AND BLOOD INSTITUTE, NIH MID-DAY SESSION

MD18 NEW OMICS FINDINGS FROM THE NHLBI PVDOMICS PROGRAM IN PULMONARY HYPERTENSION PATIENTS 12:00 p.m. - 1:00 p.m. San Diego Convention Center Room 7A-B (Upper Level) Target Audience Health providers, trainees, and researchers Objectives At the conclusion of this session, the participant will be able to: • learn about how RNAomics (genomics) of blood can aid in the discovery of mechanisms that contribute to pulmonary hypertension. • learn about metabolomics and right ventricular function in pulmonary hypertension. • learn about sleep disordered breathing-metabolomics work in relation to clinical outcomes. Pulmonary hypertension (PH) has no cure, and PH research remains a high priority for NHLBI. The current PH classification is difficult to apply clinically for precision medicine therapy. In 2014, NHLBI launched a multi-center clinical study named: Redefining Pulmonary Hypertension through Pulmonary Vascular Disease Phenomics (PVDOMICS), which includes 1 Data Coordinating Center & 6 clinical centers to conduct an observational study in PH patients. The overall goal of the PVDOMICS is to perform deep phenotyping across all PH groups and intermediate phenotypes in order to reconstruct the traditional classification and define new meaningful subclassifications. About 1200 participants have been enrolled, and the clinical and omics results from these subjects will be presented at this noon session.

ATS 2024 Conference Program • San Diego, CA

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