ATS 2024 Final Program

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215

MONDAY • MAY 20

923 The Impact of Migrant-sensitive Strategies in the Treatment of Multi-drug Resistant Tuberculosis 924 Miliary Tuberculosis: A Retrospective Cohort Study Determining Predictors of Poor Prognosis in an East London Cohort

509 Single-Cell RNA Sequencing Reveals Disease-Specific Cell-Cell Interactions in the COPD Lung 510 A Functional Multi-omics Profiling of Idiopathic Pulmonary Fibrosis Lungs Shed a New Light on Disease Mechanisms 511 IPF Aberrant Basaloid Cells Have Chromatin Accessibility Features Distinct From Other Lung Epithelial Cells 512 Spatial Transcriptomics Unravel the Mechanisms Underlying Epithelial Desquamation in Idiopathic Pulmonary Fibrosis 513 Single-cell Analysis Reveals a Pattern of Immunosenescence in Patients With Progressive Fibrotic Lung Disease 514 Single-cell Gene Expression Analysis Uncovered Fibroblast Subpopulations in Early-stage Pulmonary Fibrosis 515 Stage-specific Variations in the Fibroblast Chromatin Landscape Mediate Murine Pulmonary Fibrosis and Post-fibrotic Remodeling 516 snRNAseq of IPF Stromal Cells Reveals Dysfunctional Gene Co-expression Profile 517 A Single Nucleus RNAseq Time Course of Radiation Injury Reveals Interplay Among Injury-Associated Cell States 518 Skin Transcriptomics Are Associated With Lung Function Impairment and Specific Cell Type Enrichment in Systemic Sclerosis-related Interstitial Lung Disease 519 Applying Single Cell Profiling to Assess Drug Anti Fibrotic Properties in the Human Precision Cut Lung Slice Model of Fibrosis 520 Spatial Proteome Mapping at Single Cell Resolution in Idiopathic Pulmonary Fibrosis Using LCM-nanoPOTS Platform 521 Altered Peripheral Blood Transcriptomes in Bronchiectasis Patients With Co-morbid Cardiovascular Disease: Data From the EMBARC-BRIDGE Study 522 Single-cell Gene Transcriptomics of Peripheral Blood Reveals Cell Type-specific Molecular Associations With Quantitative CT Lung Fibrosis Extent in Hypersensitivity Pneumonitis

BASIC • TRANSLATIONAL POSTER DISCUSSION SESSION

B107 GENETIC AND TRANSCRIPTOMIC SIGNATURES IN LUNG DISEASES 2:15 p.m. - 4:15 p.m. San Diego Convention Center Room 11A-B (Upper Level) Poster Viewing 2:15-3:00 Discussion 3:00-4:15 501 MUC5B Promoter Variant Drives the Protein Signature in Early Lung Fibrosis 502 Toll-like Receptor 3 Leu412Phe: A Candidate Polymorphism in Lung Microbiome Dysregulation and Acute Exacerbation in Idiopathic Pulmonary Fibrosis Patients 503 Orthologous rs35705950 MUC5B Promoter Locus in Mice May Provide Insights into MUC5B-driven Lung Fibrosis in Humans 504 Common Variants Tollip - Associated Gives a Worse Survival in Patients With Familial Pulmonary Fibrosis 505 Spatial Transcriptomics of Developing Human Lungs Defines Cellular Phenotypes Associated With Age, Lineage, and Location 506 Single Cell Transcriptomic Analyses Reveals Dynamic Alterations and Adaptations in Pulmonary Interstitial Macrophage Populations in Response to Chronic Hypoxia 507 Epigenetic Perturbations in Upper Airway Cells in the Acute Phase of SARS-CoV-2 Infection Persistently Affect Their Transcriptional Programs 508 Alveolar Epithelial Type 1 Transcriptional Signatures in Bacterial Pneumonia-induced Acute Respiratory Distress Syndrome (ARDS) Resemble Those of COVID-19 and Idiopathic Pulmonary Fibrosis (IPF)

ATS 2024 Conference Program • San Diego, CA