ATS 2024 Final Program

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229

TUESDAY • MAY 21

BASIC • TRANSLATIONAL MINI SYMPOSIUM

BASIC MINI SYMPOSIUM

C19 CHARTING THE LUNG: INNOVATION IN MULTIOMICS 9:15 a.m. - 11:15 a.m. San Diego Convention Center Room 32A-B (Upper Level) Featured Speaker Presentation: 9:15 Single Nucleotide Resolution of Altered Transcription Factor Binding Sites in Fibrotic Human Lung Disease Oral Presentations: 9:27 Whole Blood Transcriptome in Long-COVID Patients Reveals Association With Lung Function and Differences in Immune Response: Results From the P4O2 Consortium 9:39 Transcriptional Pathways in Small Airway Basal Cells Define Niches of Goblet Cell Metaplasia in Asthma 9:51 Revealing Lung Periphery Alterations in COPD Via Spatial Transcriptomics 10:03 Spatial Transcriptomics Resolve an Emphysema-Specific Lymphoid Follicle B Cell Signature in COPD 10:15 Spatial Transcriptomic Analyses of the Aging and IPF Lungs Reveals Age and Disease Senescence Niches 10:27 Mapping Intra-pulmonary Tissue Neighborhoods Reveals Localized Fibrotic and Regenerative Motifs in Murine Pulmonary Fibrosis 10:39 Spatial Transcriptomics Analysis Reveals Pathology-specific Alveolar Niches in Pulmonary Fibrosis 10:51 Integration of High-resolution 3D Organoid Engineering and Spatial Transcriptomics as a Next-generation Drug Discovery Platform for Pathologic Lung Remodeling 11:03 Multi Omic Profiling Identifies PUFINs: Novel Long Non Coding RNAs (lncRNAs) Regulating Pulmonary Myofibroblast Activation in Fibrosis

C20 HAVING A GROWTH MINDSET: REPROGRAMMING CELLULAR PATHWAYS TO DISEASE 9:15 a.m. - 11:15 a.m.

San Diego Convention Center Room 30A-B (Upper Level)

Oral Presentations: 9:15 Disruption of Both BMP and TGF-ß Signaling in Fetal Lung Mesenchyme Has Additive Effects on Developing Congenital Pulmonary Cysts 9:27 Hydrogen Sulfide (H2S) Alleviates Effects of Hyperoxia on Mitochondrial Structure and Function in Human Developing Airway Smooth Muscle 9:39 Sex-specific Associations of DNA Methylation With Lung Function Reveal Early Life Programming of Inflammatory Pathways 9:51 Maternal High-fat Diet Programs Development of Airway Hyperinnervation and Hyperresponsiveness in Offspring Independent of Genetic Background 10:03 Stop! In the Name of (Light): Using Optogenetics to Define the Role of Parasympathetic Nerves in Allergen-induced Airway Hyperresponsiveness 10:15 Sensory Neurons Support Mast Cell Differentiation in an In Vitro Co-culture Model 10:27 Role of Novel E3 Ubiquitin Ligase RNF145 in Airway Smooth Muscle Growth and Lung Function 10:39 The Epigenetic Clock Grimage Captures a Universal Signature of Lung Aging 10:51 Survival, Growth, Respiratory Mechanics, and Neurodevelopmental Outcome in Former Preterm Lambs Treated With AVR-48 to Prevent BPD

ATS 2024 Conference Program • San Diego, CA