ATS 2024 Final Program

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244

TUESDAY • MAY 21

P660 Effect of Biologics on Biomarkers of Type 2 Inflammation in Asthma: A Review of the Literature P661 Real-world Effectiveness of Mepolizumab in the Treatment of Asthma in Japan: A Multicenter Retrospective Observational Study: J-Real-Mepo P662 The Difference in the Effectiveness of Anti-IL-5 Antibodies and Anti-IL-5r a Antibodies in Severe Bronchial Asthma P663 A Real-world Experience on New Starts Versus Biological Switchers for Tezepelumab in Severe Asthma P664 A Real-world Experience With Tezepelumab as the First Biologic Option in Severe Asthma Patients P665 Improved Lung Function Is Associated With Better Asthma Control in Children With Moderate-to-Severe Type 2 Asthma: Voyage Study P666 Impact of Half-life Extension Via YTE Modification on the Duration of Action, Efficacy, and Safety of Monoclonal Antibodies: A Systematic Literature Review

P671 Effect of Aderamastat (FP-025), A Selective MMP-12 Inhibitor, on Allergen-induced Airway Responses in Subjects With House-dust Mite Allergic Mild Asthma and Blood Eosinophilia P672 Fatty Liver Infiltration Is Associated With Decreased Lung Function in Asthmatics and Correlates With Circulating Levels of IL-6 P673 Changes in Nasal IL-1 During Acute Asthma Exacerbation in Adolescents P674 Inhibition of the Ion Channel TMEM16A With Niclosamide Inhalation Powder Reduces Inflammation, Bronchoconstriction, and Airway Hyperresponsiveness in a Large Animal Model of Asthma P675 APG808, A High-Affinity Fully Human IgG1 Monoclonal Antibody Targeting IL-4R a , Demonstrates Prolonged Half-Life in Non-Human Primates P676 IRF1 Is a Major Regulatory Transcription Factor for Immune Responses in Eosinophils P677 Transcriptomic Characterization of Type 2 Innate Lymphoid Cells From Asthma Patients in Response to Prostaglandin D 2 Metabolites P678 The Immune Regulatory Role of Subtype of Dendritic Cells in Patients With Allergic Rhinitis and Chronic Rhinosinusitis P679 Omega-3 Fatty Acid Intake Is Associated With Bronchodilator Response in Patients With Obesity and Poorly Controlled Asthma P680 Oxidant-induced Alteration of Fibrotic Markers in Airway Fibroblasts Isolated From Patients With Asthma and Obesity P681 Human Blood Neutrophils and Eosinophils Display Distinct Proteolytic Signatures P682 Decoding the Transcriptional Response to Severe Exacerbations Among African-american Individuals With Asthma P683 Patterns of Specific Allergen IgE Positivity in Allergic Bronchopulmonary Aspergillosis P684 The Mutual Relationship Between Type- 2 Inflammation Signature Biomarkers and Serum Periostin Is Disease-dependent P685 Examining the Effect of ILC2s on Airway Smooth Muscle Hypercontractility in Asthma

BASIC • CLINICAL • TRANSLATIONAL THEMATIC POSTER SESSION

C35 INNOVATIVE BIOMARKERS TO

IDENTIFY ALLERGIC INFLAMMATION

9:15 a.m. - 4:15 p.m.

San Diego Convention Center Area F (Hall A-B2, Ground Level)

Viewing: Posters will be on display for entire session Discussion: 11:30-12:30 Discussionwith facilitators, authors, andattendees 12:30-1:15 Authorswill beby their posters for individual discussionwithattendees P668 GLP-1 Agonists Reduce Functional Endoscopic Sinus Surgery Rates in Chronic Rhinosinusitis Patients With Obesity P669 Transient Receptor Potential A1 Channel Contributes to Enhanced Innate Airway Inflammation After Cold-air Exposure P670 Serum CC16 in Childhood and Adolescence: Associations With Lung Function Development and Asthma

ATS 2024 Conference Program • San Diego, CA