ATS 2024 Final Program

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SUNDAY • MAY 19

27

10:03 Disease Phenotype in Bronchiectasis (NTM- and NTM+) Is Associated With Lower Airway Dysbiosis and Neutrophil Extracellular Traps 10:15 Intermittent Versus Daily Treatment for Noncavitary Nodular Bronchiectatic Mycobacteria Avium Complex Lung Disease With Rifampicin, Ethambutol, and Clarithromycin (iREC): An Open-label, Multicenter, Randomized Controlled Trial 10:27 Investigating the Impact of Azithromycin on the Lung Microbiome and Immune Response in Patients With Bronchiectasis 10:39 Clinical Efficacy of Anti-glycopeptidolipid-core IgA Test for Screening Nontuberculous Mycobacterial Infection in Bronchiectasis: A Multicenter European Study 10:51 Net and Cell Count Differentials Among NTM +/- Bronchiectasis Patients With Cavitary and Non-cavitary Disease Featured Speaker Presentation: 11:03 Breathing into the Future: Innovations in Bronchiectasis and NTM Management A17 COPD CHRONICLES: DECODING THE PATHOGENESIS OF A COMPLEX DISEASE 9:15 a.m. - 11:15 a.m. Marriott Marquis San Diego Marina Grand Ballroom 2-4 (Lobby Level, North Tower) Featured Speaker Presentation: 9:15 Deciphering Lung Immunity in Emphysema: One T Cell at a Time Oral Presentations: 9:27 Muc5b Suppresses Alveolar Regeneration by Club Cells in COPD 9:39 Effect of Mucus Plugging on Bronchial Gene Expression 9:51 Paraseptal Emphysema Is Characterized by a TLR-Th17-driven Adaptive Immune Response BASIC • TRANSLATIONAL MINI SYMPOSIUM

10:03 Genetically Driven Cell Specific Splicing of

CROCCP2 Is Associated With COPD Case Control Status

10:15 X Chromosome Methylation Patterns and Sex-dosage Imbalance: Implications for COPD Susceptibility and Severity 10:27 Novel Role of the Chromatin Remodeling Protein HMGN5 in Driving COPD Susceptibility 10:39 Peroxiredoxin 6 Protects Pulmonary Epithelial Cells From Cigarette-related Ferroptosis Via Inhibition of Oxidative Stress 10:51 Failure of Alveolar Regeneration Following Cigarette Smoke-induced Chronic Lung Injury 11:03 Inhibition of Membrane-bound MUC1 Mucin Attenuates Cigarette Smoke-induced Mucus Hypersecretion A18 FIXING WHAT’S BROKEN: NOVEL THERAPEUTICS FOR LUNG REMODELING 9:15 a.m. - 11:15 a.m. Oral Presentations: 9:15 A First-in-human Study in Healthy Volunteers Investigating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5055, A Novel Oral Porcupine Inhibitor Under Development as a Treatment for Pulmonary Fibrosis 9:27 Therapeutic Efficacy of Olaparib in a Sheep Model of Pulmonary Fibrosis 9:39 Mimecan and a Functional Fragment Hereof as a Novel Regenerative Agent for COPD 9:51 Impact of Mepolizumab on Airway Remodelling in Severe Eosinophilic Asthma 10:03 Effect of Dupilumab on Pulmonary Vascular Volume in Patients With Moderate-to-Severe Asthma San Diego Convention Center Room 8 (Upper Level) BASIC • TRANSLATIONAL MINI SYMPOSIUM

ATS 2024 Conference Program • San Diego, CA