ATS 2024 Final Program

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327

WEDNESDAY • MAY 22

406 CAR Peptide Targeted Liposomes Loaded With an Admixture of Fasudil and DETA Nonoate for the Treatment of Pulmonary Arterial Hypertension 407 DHCR7 Deficiency Promotes 7ß-hydroxycholesterol Accumulation and Endothelial Apoptosis in Pulmonary Hypertension 408 Canagliflozin, An SGLT2 Inhibitor, Prevents Lung Remodeling in Chronic Left Ventricular Failure 409 Advanced 3D Arterial Microvessel-on-Chip to Model Pulmonary Arterial Hypertension (PAH) 410 STIM1 Contributes to Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension 411 Mitochondrial c-Src Regulates Right Ventricular Fibroblast Metabolic Function and Activation in Pulmonary Hypertension 412 Telangiectatic Pulmonary Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia 413 Reversal of Inflammatory Reprogramming at Single Cell Resolution by Vasodilator Agents in Pulmonary Arterial Hypertension 414 Hymecromone Improves Functional Performance in Individuals With Group 3 Pulmonary Hypertension

303 Assessing Aberrations of Pulmonary Immune Cells in Bronchopulmonary Dysplasia Using Single Nuclear Sequencing and Multiplexed Immunofluorescence (MxIF) Microscopy 304 Differences in the Early Airway Expression of Thrombospondin-1 Protein in Extremely Low Birth Weight Infants With and Without Bronchopulmonary Dysplasia 305 Single Cell Transcriptomics of Airway Cells From Primary Ciliary Dyskinesia (PCD) Patients Reveal Activation of Novel Motile Cilia Dedicated Pathways 306 Peripheral Blood Gene Expression Profiles in Childhood Interstitial Lung Disease 307 Plasma Proteomics Identifies Molecular Features of Bronchiectasis in Cystic Fibrosis 308 Plasma Proteomic Profiles at Age 1 Year Capture Disruption Related to Respiratory Infection Risk 309 A Prognostic Proteomic Signature of Immune Dysregulation Is Present at Onset of Multiple Organ Dysfunction Syndrome in Pediatric Patients With and Without Sepsis 310 Derivation, Validation, and Transcriptomic Assessment of Pediatric Septic Shock Molecular Phenotypes Identified Through Latent Profile Analyses 311 Association of 17q12-q21 Asthma Risk Locus With Severity of Infant Respiratory Syncytial Virus Infection 312 Rhinovirus (HRV) Infection Drives Severe Wheezing Episodes in Toddlers: Viral Metagenomic Analysis in the WINDOWS Study 313 Differential Expression of MicroRNA 24-3p and Frequency of Awakenings Due to Asthma Symptoms in Two Independent Cohorts 314 A Novel Pediatric Cystic Lung Disease Caused by CCR2 Deficiency 315 Bi-allelic LAMP3 Variants in Three Children With Interstitial Lung Disease: Evidence of a Novel Disease-gene Association 316 Rapid Whole Genome Sequencing (WGS) in Diagnosing the Etiology of Refractory Pulmonary Hypertension of the Newborn (PPHN) 317 Recurrent Pneumothorax: A New Manifestation of Filamin A (FLNA) Deficiency

BASIC • CLINICAL • TRANSLATIONAL POSTER DISCUSSION SESSION

D28 PEDIATRIC PULMONOLOGY

BENCH-TO-BEDSIDE: GENETICS, WHOLE-EXOME SEQUENCING, AND OMICS

8:15 a.m. - 10:15 a.m.

San Diego Convention Center Room 28C-E (Upper Level)

Poster Viewing

8:15-9:00 9:00-10:15

Discussion

301 Pulmonary Microbiome and Transcriptome Signatures Reveal Distinct Biologic States of Lung Injury in Two Cohorts of Pediatric Stem Cell Transplant Patients 302 A Transcriptome-wide Association Study of Sex Effects on Nasal Epithelial Gene Expression in Two Cohorts of Children and Adolescents

ATS 2024 • San Diego, CA