ATS 2024 Final Program

Click on the session title to view the speakers

329

WEDNESDAY • MAY 22

502 IL-33/ST2 Regulates Tissue Remodeling Via MAPK and NF- k B Pathways in Nasal Polyp 503 Targeting BDNF/arginase Pathways in Airway Remodeling 504 Establishing a 3D Vascularized Triculture Model of the Human Lung Airways Using a Digital Light Processing Bio-printer 505 TSLP, IL-4 and IL-13 Increase Transcriptional Programs Associated With Hypercontractility in Human Airway Smooth Muscle 506 Hyperoxia-induced Inflammatory Senescence Phenotype in Human Fetal Airway Smooth Muscle Is Targetable With Senolytic Therapy 507 Antagonizing N-Cadherin in Airway Smooth Muscle Cells Confers Bronchoprotection 508 Effect of Diet-induced Obesity and Genetic Deficiency of G Protein-coupled Receptor 1 on Ozone-induced Increases in Airway Responsiveness 509 Rhinovirus C15 (RV-C15) Infection of Airway Epithelia Attenuates Bronchodilator Responsiveness Via Production of Vascular Endothelial Growth Factor (VEGF) 510 Nicotine-induced ER Stress and ASM Cell Proliferation Is Mediated by a 7nAChR and Chaperones-RIC-3 and NACHO 511 Sex-steroids Differentially Skew Leptin/Adiponectin Signaling and Their Effects on Airway Smooth Muscle Cell Remodeling 512 Inhaled S-nitrosoglutathione (GSNO) Can Serve as an Acute Bronchodilator in Human Asthma, Augmenting the Effect of Albuterol 513 Desensitization of the Muscarinic M3 Receptor Inhibits Airway Hyperresponsiveness in a Murine Model of Asthma 514 PD-102807, A Beta-arrestin Activator, Inhibits the Contraction of Airway Smooth Muscle 515 Prematurity and Low Birth Weight Does Not Affect Airway Smooth Muscle Thickness in Sudden Infant and Early Childhood Death 516 Piezo Channels Modulate Stretch-induced Remodeling and Calcium Regulation in Human Lung Fibroblasts

517 Crosstalk Between Piezo Channels and the STIM1-Orai1 Pathway Mediates Mechanical Stretch-induced Increases in Intracellular Calcium Signaling in Human Airway Smooth Muscle Cells 518 Diacylglycerol Generated by Diacylglycerol Kinase Inhibition Reduces Airway Smooth Muscle Cell Contraction 519 Role of GPRC5A in Human Airway Smooth Muscle Remodeling 520 Airway Smooth Muscle Cell Phenotype Is Determined by Myocardin-Elk-1 Competition for Serum Response Factor 521 Trefoil Factor 3 (TFF3) Attenuates ß 2 -agonist Responsiveness of Human Airway Smooth Muscle (HASM) and Precision Cut Lung Slices (hPCLS) 522 Assessment of Albuterol Response Reveals Sex Dependent Bronchodilation in a Murine Model of Allergic Asthma 523 Pitavastatin Induces Airway Smooth Muscle Relaxation Through the Actin-severing Action of Cofilin: A Role for Inhaled Statins in Acute Bronchodilation 524 Investigating Genome Wide Dna Methylation in Airway Smooth Muscle Cells From Asthmatic and Non-asthmatic Donors 525 Activation of PIEZO1 Evokes Calcium Flux and Promotes Human Airway Smooth Muscle Cell Relaxation

PEDIATRIC CLINICAL CORE CURRICULUM

PCC3 PEDIATRIC CLINICAL CORE CURRICULUM 3 9:30 a.m. - 10:30 a.m.

San Diego Convention Center Ballroom 20A (Upper Level)

Target Audience: All attendees Objectives At the conclusion of this session, the participant will be able to: • discuss the management of pediatric ARDS, massive hemoptysis, and severe asthma in the ICU

ATS 2024 • San Diego, CA