Final-Program-ATS-2023-AP.vp

SUNDAY • MAY 21

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Objectives At the conclusion of this session, the participant will be able to: • inform the clinicians and researchers about specific areas of debate in management of common and burdensome respiratory conditions: 1) Asthma; 2) OSA; 3) Fibrotic lung disease and 4) ARDS • apply state of the science to help the audience decide on appropriate 1) management of severe Asthma with biologics; 2) use of the AHI in OSA patients; 3) therapeutics in lung fibrosis and 4) treatment of ARDS for their patients • identify key gaps for conditions mentioned in objectives 1 and 2 that should inform future research The pulmonary, critical care, and sleep communities have made progress toward evidence-based care and developing novel therapies for “incurable” diseases. However, recent data challenge current approaches and create uncertainty about the research and management approaches to highly burdensome respiratory conditions. These controversies include 1) management of severe asthma, 2) apnea-hypopnea index as a prognostic marker in OSA, 3) correcting cellular aging in fibrotic and inflammatory diseases, and 4) targeting oxygenation during ventilation of acute respiratory distress syndrome. This session will address the state of the science and evidence for aspects of managing these conditions to inform clinical decision-making and future research. Chairing: A. Zinchuk, MD, MHS, BS, New Haven, CT A.M. Esper, MD, MS, ATSF, Atlanta, GA M. Rojas, MD, Columbus, OH M. Wechsler, MD, Denver, CO N.A. Shah, MD, MPH, MSci, New York, NY 2:15 Introduction to Debate 1: Biologics Overlap in Asthma M. Wechsler, MD, MSc, Denver, CO 2:18 Truth: Biologics Can Be Combined and Overlapped in Severe Asthma M. Kraft, MD, ATSF, New York, NY 2:27 Myth: Biologics Can Be Combined and Overlapped in Severe Asthma P. Akuthota, MD, ATSF, La Jolla, CA 2:36 Summary and Audience Response Results (Debate 1) M. Wechsler, MD, MSc, Denver, CO 2:38 Introduction to Debate 2: Utility of the AHI N.A. Shah, MD, MPH, MSci, New York, NY 2:40 Truth: The AHI Should Be Used in Prognostication and Treatment of OSA A. Malhotra, MD, ATSF, La Jolla, CA 2:49 Myth: The AHI Should Be Used in Prognostication and Treatment of OSA S.S. Redline, MD, MPH, Boston, MA 2:58 Summary and Audience Response Results (Debate 2) A. Zinchuk, MD, MHS, BS, New Haven, CT

Social determinants of health (SDOH) are the conditions where people live, learn, work, and play. SDOH drive disparities in health outcomes, but most studies have focused on documenting the role of the SDOH rather than on identifying interventions that directly influence the SDOH. Environmental factors are both a component of and also a potential target for intervention on the SDOH. This session, which will include examples from both high income and low and middle income countries, will discuss how environmental factors are a core component of the SDOH and show that environmental interventions can change the SDOH and address health disparities. Chairing: P.S. Lai, MPH, MD, ATSF, Boston, MA R. Bascom, MD, MPH, Hershey, PA O.B. Ozoh, MBBS, ATSF, MSc, Lagos, Nigeria 2:15 How Do We Quantify the Social Determinants of Health? J.R. Balmes, MD, ATSF, San Francisco, CA 2:30 Environmental Context and Barriers to Asthma Inhaler Use in High Income vs. Low and Middle Income Countries I.L. Riley, MD, MPH, Durham, NC 2:45 Household Energy Use in Low and Middle Income Countries Affects Lung Health and Perpetuates Poverty O.B. Ozoh, MBBS, ATSF, MSc, Lagos, Nigeria 3:00 Climate Change Exacerbates Health Inequalities Due to Household Energy Insecurity D. Hernandez, PhD, New York, NY 3:15 Should I Pay for Food, Rent, or Inhalers? Community Linkage Resource Programs and Pediatric Asthma Exacerbations in the United States A. Martinez, MD, MPH, San Francisco, CA 3:30 Can a Household Energy Intervention Change the Social Determinants of Health? Solar Lighting in Rural Uganda P.S. Lai, MPH, MD, ATSF, Boston, MA

BASIC • CLINICAL • TRANSLATIONAL SCIENTIFIC SYMPOSIUM CME Credits Available: 1.5

A90 MYTHS OR TRUTHS: CONTROVERSIES IN RESPIRATORY MEDICINE, THE NEW FRONTIER Assemblies on Sleep and Respiratory Neurobiology; Allergy, Immunology and Inflammation; Critical Care; Respiratory Cell and Molecular Biology 2:15 PM - 3:45 PM Walter E. Washington Convention Center Ballroom B (Level 3) Target Audience Clinicians and researchers working in the fields of critical care, fibrotic and inflammatory lung disease, asthma, allergy and sleep medicine

ATS 2023 • Washington, DC