Final-Program-ATS-2023-AP.vp

MONDAY • MAY 22

137

10:24 Wnt Signaling in Mesenchymal Vascular Progenitor (MVPC) Drives Adaptive Angiogenesis During Fibrosis and Regulates Pulmonary Tissue Repair/ E. Mason, Denver, CO 10:36 Single Nuclear RNAseq of Differentially Affected IPF Lung Uncovers Potential Cellular Origins of Aberrant Basaloid Cells/ T.S. Adams, New Haven, CT 10:48 Sex-dependent Susceptibility to Pulmonary Fibrosis Is Associated With Reduction in ASK1 Activation and Autophagy in Aged Mice/ S. Dos Santos Valenca, Lexington, KY

10:24 Real-world Effectiveness of Portable Air Cleaners in Reducing Home Particulate Matter Concentrations/ F.T. Lu, Piscataway, NJ 10:36 Effectiveness of WeChat-Based Smoking Cessation Intervention Among Chinese Male Workers Exposed to Dust: A Randomized Controlled Trial/ R. Li, Kunming, China

Featured Speaker: 10:48

Closing Remarks: Multi-pronged Approaches to Reduce Harmful Impacts of Pollutants/ N.N. Hansel, Baltimore, MD

BASIC • CLINICAL • TRANSLATIONAL MINI SYMPOSIUM

BASIC • CLINICAL • TRANSLATIONAL MINI SYMPOSIUM

B19

PLAYING THE TIKI-TAKA: THE CELL CROSSTALK GAME IN LUNG REPAIR

B20

THE ONLY CONSTANT IS CHANGE: NEW INSIGHTS INTO AIRWAY REMODELING

9:00 a.m. - 11:00 a.m.

Walter E. Washington Convention Center Room 202 B (Level 2)

9:00 a.m. - 11:00 a.m.

Walter E. Washington Convention Center Room 150 A-B (Street Level)

Chairing: A.L. Mora, MD, Columbus, OH

J.L. Larson-Casey, PhD, Birmingham, AL D. Lagares, PhD, MSc, Boston, MA

Chairing: R. Gosens, PhD, Groningen, Netherlands

J.R. Johnson, PhD, Birmingham, United Kingdom

Featured Speaker: 9:00 Role of Transitional AECs in Pulmonary Fibrosis/ R.L. Zemans, Ann Arbor, MI Oral Presentations: 9:12 GPR87 Regulates Epithelial Repair During Pulmonary Fibrosis/ F.J. Kamga Gninzeko, Nashville, TN 9:24 IL11 Causes Alveolar Type 2 Pneuomocyte Dysfunction and Inhibits Alveolar Regeneration in the Damaged Lung/ B. Ng, Singapore, Singapore 9:36 Epithelial HIF Inhibition Enables Adaptive Repair and Alveolar Regeneration in Chronic Lung Injury/ A.S. Mccall, Nashville, TN 9:48 Disrupted Alveolar Epithelial Proteostasis Drives AT2 Cell Phenotype Changes in Murine and Human Preclinical SP-C Mutation Models of Pulmonary Fibrosis/ J. Katzen, Philadelphia, PA 10:00 Immune Checkpoint Blockade Is Associated With Improved Alveolar Epithelial Repair Responses in a Humanized CTLA4 Murine Model/ S. Yadav, New Orleans, LA 10:12 Ectopic MUC5B Expression in SFTPC-Positive Alveolar Epithelial Cells in Subjects Without Lung Fibrosis/ T. Kato, Chapel Hill, NC

Oral Presentations: 9:00 Development of Airway Sensory Hyperinnervation and Reflex Hyperresponsiveness in Offspring of Obese Mothers/ K. Williams, Portland, OR 9:12 Oxidized Phosphatidylcholine Promotes Protein Kinase C-mediated B 2 Adrenoceptor Dysfunction to Induce Bronchodilator Insensitivity/ J.M. Vaghasiya, Winnipeg, Canada 9:24 Recruited Lung Macrophages Contribute to Airway Remodeling and Airway Hyperresponsiveness in a Mouse Model of Severe Allergic Airway Inflammation/ B.W. Lewis, Columbus, OH 9:36 Senescence Induction in Aging Asthmatic Airway Cells/ A. Aghali, Rochester, MN 9:48 Hyperoxia Induces Senescence in Developing Human Airway Smooth Muscle Cells/ A. Aghali, Rochester, MN 10:00 Defining the Prostanoid Component in Mast Cell-dependent Constriction of Isolated Human Small Airways/ J. Säfholm, Stockholm, Sweden 10:12 CD38 Promotes Th17 Inflammation in Aged Mice With Severe Allergic Airway Inflammation/ M.L. Ford, Columbus, OH 10:24 The Phenotypic Effect of Sex Chromosomes Versus Sex Hormones in a Mouse Model of Allergic Asthma/ C.D. Ekpruke, Bloomington, IN

ATS 2023 • Washington, DC