Final-Program-ATS-2023-AP.vp

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TUESDAY • MAY 23

9:00 Current Knowledge on the Effects of Opioids on Sleep Quality, Sleep Architecture, Sleep-Disordered Breathing, Sleep Apnea Endotypes D.J. Eckert, PhD, Bedford Park, Australia 9:15 Sleep Deficiency Across the Trajectory of OUD: Neuro-Biologic, Neuro-Psychiatric, and Social-Ecologic Mechanisms H.K. Yaggi, MD, New Haven, CT 9:30 Targeting Insomnia in OUD: CBTi and Leveraging the Orexin System C. Hsiao, MD, New Haven, CT 9:45 PAP Therapies for Sleep-Disordered Breathing OUD S. Chowdhuri, MD, MS, ATSF, Detroit, MI 10:00 Novel Pharmacologic Treatments Targeting Control of Breathing in Opioid Use: Intranasal Leptin, Ampakines, and Other Potential Targets V.Y. Polotsky, MD, PhD, Baltimore, MD 10:15 Sleep Deficiency as a Core Feature of OUD and

10:10 Argument 2: There Is a Better Alternative to Integrating Patients with Long COVID into Pulmonary Rehabilitation D. Wade, MD, Oxford, United Kingdom 10:20 Discussion Session

BEHAVIORAL • CLINICAL • TRANSLATIONAL SCIENTIFIC SYMPOSIUM

CME Credits Available: 1.5 MOC Points Available: 1.5

C10 OPIOID USE DISORDER, SLEEP DEFICIENCY, AND VENTILATORY CONTROL: BIDIRECTIONAL MECHANISMS AND THERAPEUTIC TARGETS Assembly on Sleep and Respiratory Neurobiology 9:00 AM - 10:30 AM Walter E. Washington Convention Center Room 145 A-B (Street Level) Target Audience Sleep providers, patients with sleep deficiency, opioid use disorder, Those who take care of patients on opioids, those interested in sleep phenotypes and control of breathing Objectives At the conclusion of this session, the participant will be able to: • at the end of this session, the participants will have an improved understanding of the bidirectional mechanisms between opioid use disorder (OUD) and sleep deficiency. • describe efforts to target sleep deficiency and control of breathing with therapeutic interventions to promote long-term healthy recovery among patients with OUD. • outline an actionable research agenda to evaluate the basic mechanisms of the relationship between sleep deficiency and OUD and the potential for behavioral, pharmacologic, and positive airway pressure treatments to improve OUD treatment outcomes. This session will highlight the bidirectional mechanisms between opioid use disorder (OUD) and sleep deficiency. It will discuss how targeting sleep deficiency and control of breathing with therapeutic interventions can promote long-term, healthy recovery among patients in OUD treatment. Current knowledge on the effects of opioids on sleep architecture, sleep-disordered breathing, sleep apnea endotypes, ventilatory control, and and clinical practice are highlighted. Finally, an actionable research agenda is provided to evaluate the basic mechanisms of the relationship between sleep deficiency and OUD and the potential for behavioral, pharmacologic, and positive airway pressure treatments targeting sleep deficiency to improve OUD outcomes. Chairing: J.E. Orr, MD, La Jolla, CA T. Kendzerska, MD, PhD, Ottawa, Canada

Recovery: A Research Agenda A. Laposky, PhD, Bethesda, MD

BEHAVIORAL • CLINICAL • TRANSLATIONAL SCIENTIFIC SYMPOSIUM CME Credits Available: 1.5 ADVANCING CLINICAL ISSUES TO ATS AND CAPITOL HILL: THE OXYGEN THERAPY EXEMPLAR

C11

Assemblies on Clinical Problems; Environmental, Occupational and Population Health; Nursing; Pediatrics; Pulmonary Rehabilitation; International Health Committee; Health Policy Committee 9:00 AM - 10:30 AM Walter E. Washington Convention Center Room 147 A-B (Street Level) Target Audience All ATS Members (This session is beneficial for all members as it provides a framework for taking a clinical issue, addressing it through ATS clinical, research and health policy groups, then engaging members in advocating for legislative changes. Objectives At the conclusion of this session, the participant will be able to: • describe two challenges or barriers to patients’ oxygen therapy as related to CMS regulations and/or DME Companies. • incorporate approaches from ATS Clinical Oxygen Guidelines to address patients’ oxygen therapy concerns. • describe two strategies ATS members can use to effectively advocate for legislation related to oxygen therapy.

ATS 2023 • Washington, DC