Final-Program-ATS-2023-AP.vp

TUESDAY • MAY 23

223

Target Audience Adult and pediatric pulmonologists, critical care providers, immunologists, cell biologists Objectives At the conclusion of this session, the participant will be able to: • better understand and incorporate current and novel biomarkers for respiratory infection correlates of protection or severity, including SARS-CoV-2, into current practice • gain knowledge of novel techniques for tracking pathogen-host interactions over the course of infection, including single cell approaches and cell-free analyses • discuss comprehensive cohort study design that includes molecular, genetic, environmental, and epidemiological variables as components of immune modeling for host pathogenesis Findings presented will highlight novel correlates of severity and protection during respiratory illness, including SARS-CoV-2 infection, that could be useful as biomarkers for viral illness outcome. The session will explore new aspects of the host pathogen interface that could be harnessed as a clinical tool and lead to host-targeted therapeutics. What biomarkers can be used to determine individuals at higher risk of E.K. Allen, PhD, Memphis, TN 9:05 Host-Microbiome Interactions in Early in Life - Key to Respiratory Infections? Debby Bogaert, MD, PhD, Edinburgh, UK 9:20 Q&A 9:25 SARS-CoV-2 Repeat Infections and Breakthroughs: Correlates of Immunity and Determinants of Severity A. Gordon, PhD, Ann Arbor, MI 9:40 Q&A 9:45 Severe Respiratory Viral Infection Results in Persistent Immune Activation of Lung Fibroblasts Associated with 10:00 Q&A 10:05 Profiling the Mucosal TCR Repertoire Landscape During Severe Pneumonia L. Morales-Nebreda, MD, Chicago, IL 10:20 Q&A Prolonged Respiratory Distress D.F. Boyd, PhD, Santa Cruz, CA severe illness outcome from respiratory viral infection? Chairing: A. Rogers, MD, MPH, ATSF, Stanford, CA T. Flerlage, MD, Memphis, TN E.K. Allen, PhD, Memphis, TN P. Thomas, PhD, Memphis, TN 9:00 Immunology in Context

Do your patients face difficulty in getting adequate access to supplemental oxygen? This session will cover novel oxygen delivery systems for outpatient use and upcoming innovations in oxygen delivery. A particular focus will include current barriers to oxygen delivery, regulatory limitations which impair access to adequate oxygen, and ATS advocacy needed towards legislative change. ATS’s involvement in advancing this clinical issue to health policy change will be addressed. Finally, the session covers the next frontier in access to home respiratory support, highlighting patients’ and providers’ challenges after the recent recall of non-invasive ventilation devices and advocating for those issues. Chairing: N.A. Kolaitis, MD, MS, San Francisco, CA S.S. Jacobs, RN, MS, Stanford, CA 9:00 Introduction of the Session N.A. Kolaitis, MD, S, San Francisco, CA 9:02 Setting the Tone: Capturing the Patient’s Perspective 1 N.A. Kolaitis, MD, MS, San Francisco, CA 9:04 Setting the Tone: Capturing the Patient’s Perspective 2 J.M. Rommes, PhD, West Des Moines, IA 9:10 Listening to the Demands for Improvements: Innovations in Oxygen Delivery D. Hayes, MD, MS, MEd, ATSF, Cincinnati, OH 9:25 It’s Reality for Our Patients: Challenges/Barriers Related to CMS Regulations and DME Companies J.A. Krishnan, MD, PhD, ATSF, Chicago, IL 9:40 ATS Means Family and Family Means Nobody Gets Left Behind: ATS Responses to Oxygen issues S.S. Jacobs, RN, MS, Stanford, CA 9:50 To Capitol Hill and Beyond: ATS Government Relations and Your Advocacy on Capitol Hill G. Ewart, MHS, Washington, DC 10:00 Access, Recall and Care, Oh My!: The Next Frontier in Advocacy H. Schotland, MD, ATSF, New York, NY 10:15 QueMstions and Answers S.J. Crowder, PhD, RN, ATSF, Indianapolis, IN

BASIC • CLINICAL • TRANSLATIONAL SCIENTIFIC SYMPOSIUM CME Credits Available: 1.5

C12

IMMUNOLOGY IN CONTEXT: MECHANISMS AND BIOMARKERS THAT DETERMINE VIRAL DISEASE SEVERITY

Assemblies on Allergy, Immunology and Inflammation; Pediatrics; Pulmonary Infections and Tuberculosis; Respiratory Cell and Molecular Biology; Section of Genetics and Genomics 9:00 AM - 10:30 AM Walter E. Washington Convention Center Room 152 A-B (Street Level)

ATS 2023 • Washington, DC