Final-Program-ATS-2023-AP.vp

TUESDAY • MAY 23

227

BASIC • TRANSLATIONAL MINI SYMPOSIUM

CLINICAL • TRANSLATIONAL POSTER DISCUSSION SESSION

C19

C21

EMERGING MECHANISMS IN COPD AND ASTHMA

“CUTTING” EDGE: CLINICAL STUDIES IN INTERVENTIONAL PULMONARY AND PLEURAL DISEASE

9:00 a.m. - 11:00 a.m.

Walter E. Washington Convention Center Room 202 B (Level 2)

9:00 a.m. - 11:00 a.m.

Walter E. Washington Convention Center Room 206 (Level 2)

Chairing: F. Polverino, MD, PhD, Houston, TX M.R. Faner, PhD, BSc, Barcelona, Spain E.R. Neptune, MD, ATSF, Baltimore, MD Featured Speaker: 9:00 Immune Targeted Therapies in COPD and Asthma/ A.O. Yildrim, Neuherberg, Germany Oral Presentations: 9:12 Single Cell RNA Sequencing Identifies Dysfunctional Alveolar Type II Subsets Derived by Club Cells in Chronic Obstructive Pulmonary Disease/ Y. Hu, Aurora, CO 9:24 Loss of CD55 in Alveolar Type 2 Epithelial (AT2) Cells Results in Decreased Cell Proliferation and Increased Lung Complement Deposition During Cigarette Smoking/ E. Lundberg, Denver, CO 9:36 Loss of P73 Is Common in Chronic Obstructive Pulmonary Disease Small Airways, Is Induced by Cigarette Smoke, and Contributes to Emphysema/ B.W. Richmond, Nashville, TN 9:48 Cellular and Molecular Mechanisms Underlying FGF10-mediated Reversion of Experimental Emphysema and Pulmonary Hypertension in Mice/ S. Hadzic, Giessen, Germany 10:00 Gene Environment Interaction in Chronic Obstructive Pulmonary Disease: Involvement of a Nicotinic Receptor Gene Polymorphism/ L. Massara, Lille, France 10:12 Early COPD Risk Is Associated With Decreased Airway Basal Progenitor Function and Altered Cellular Bioenergetics in Younger Smokers/ K. Lkhagvadorj, Aurora, CO 10:24 Steroid-resistant Severe Asthma and Fatal Asthma Small Airways Are Defined by Mucus Plugging and Heterogeneous MUC5AC Expression/ S. Schworer, Chapel Hill, NC 10:36 Single-cell Transcriptomic Analysis Reveals an Altered Bronchial Epithelial Cell Differentiation in Asthma/ A.C. Gay, Groningen, Netherlands 10:48 Mitochondrial Adenine Nucleotide Translocase 2 (Ant2) Regulates Alveolar Epithelial Cell Senescence and Repair in COPD/ C.R. Kliment, Pittsburgh, PA

Poster Viewing

9:00-9:45 9:45-11:00

Discussion

Chairing: S. Tomassetti, RCP, Florence, Italy J. Thiboutot, MD, Baltimore, MD A. Gangemi, MD, Philadelphia, PA 701 Bronchial Rheoplasty Reduces Goblet Cell Hyperplasia and Airway Inflammation in Patients With Chronic Bronchitis/ A. Valipour, Vienna, Austria 702 Emphysema Heterogeneity Impacts Response to Endobronchial Valve Treatment/ S. Roodenburg, Groningen, Netherlands 703 Endobronchial Valve Placement and Functional Lung Imaging/ K. Nakrani, Miami, FL 704 Pre-interventional Evaluation of Lobar Function of Endobronchial Valve Candidates/ A.B. Karanam, Philadelphia, PA 705 Effect of Pre-procedure Cardiopulmonary Exercise Capacity and High Resolution Computerized Tomography Emphysema Pattern on Outcomes in Bronchoscopic Lung Volume Reduction/ A.B. Karanam, Philadelphia, PA 706 Importance Of Right Heart Catheterization In The Assessment For Inclusion Criteria Regarding Endobronchial Valve Placement In Patients With Echocardiography Suggesting Probability Of Pulmonary Hypertension/ K. Alsheimer, Sayre, PA 707 Response to Endobronchial Valve Treatment: It Is All About the Target Lobe/ J. Hartman, Groningen, Netherlands 708 Temporary Worsening of Resting Hypoxemia After Bronchoscopic Lung Volume Reduction/ R.J. Vender, Philadelphia, PA 709 Referral Patterns After Bronchoscopic Lung Volume Reduction Evaluation/ A.J. Gangemi, Philadelphia, PA 710 Sequential Bilateral Bronchoscopic Lung Volume Reduction in Patients With Advanced Emphysema/ A.J. Gangemi, Philadelphia, PA 711 Endobronchial Valves for Prolonged Air Leaks: A Systematic Review and Meta-analysis/ Z. Umar, Queens, NY

ATS 2023 • Washington, DC