Final-Program-ATS-2023-AP.vp

234

TUESDAY • MAY 23

1021 Inhaled FGF19 Therapy in Pulmonary Fibrosis/ M. Ghanem, Paris, France 1022 Metabolic Alterations in Bleomycin Induced Pulmonary Fibrosis in Mice/ M.A.T. Freeberg, Richmond, VA 1023 Fibroblasts From Idiopathic Pulmonary Fibrosis Driving an Alterated Phenotype in Healthy Alveolar Type II Cells in 3D Organoid/ J.A. Ovando Ricardez, Columbus, OH 1024 Cell-subpopulations in Upper and Lower IPF Lobe at Spatial Transcriptomics Resolution/ J.A. Ovando Ricardez, Columbus, OH 1025 Thyroid Hormone Receptor ß Agonist Sobetirome Attenuates Pulmonary Fibrosis Via Promoting Hyperplastic Alveolar Epithelial Type 2 Cells Differentiation Into Type 1 Cells/ G. Yu, Xinxiang, China

1005 Modelling Lung Aging in a Dish - Prolonged 3D Culture Causes Telomere Length Attrition in Induced Pluripotent Stem Cell-derived Type 2 Alveolar Epithelial Cells/ A. Schweikert, Dublin, Ireland 1006 Fibroblasts From Hermansky-pudlak Syndrome Mice Contribute to Altered Growth in Alveolar Organoids/ B. Banaschewski, Philadelphia, PA 1007 Use of an Organoid Model to Evaluate Drug Antifibrotic Responses in Interstitial Lung Diseases/ K.G. Dsouza, Birmingham, AL 1008 Autocrine LIF/LIFR Loop Amplifies Multiple Pro-fibrotic Programs in Lung Fibroblasts and LIFR Blockade Reduces Fibrosis in Human IPF PCLS/ H.N. Nguyen, Boston, MA 1009 Tissue-specific Single Cell RNA Sequencing of Human Lung Sub-compartments Defines Spatial Heterogeneity of Interstitial Macrophages and Other Leukocytes/ P. Hume, Denver, CO 1010 High-dimensional Analysis of Cell-cell Signaling in Pulmonary Biology and Disease Using Niches/ M.S.B. Raredon, New Haven, CT 1011 Fibrotic Cocktail Treated Human Precision Lung Slices Replicate the Cellular Diversity of the IPF Lung/ A. Justet, New Haven, CT 1012 Preservation of Relevant Signaling Pathways in the Living Precision Cut Lung Slices of Patients With Pulmonary Fibrosis/ C. Hesse, Hannover, Germany 1013 Dissecting Trigger-Specific Cellular Senescence in Human Precision-Cut Lung Slices/ D. Beaulieu, Pittsburgh, PA 1014 Durable Alveolar Engraftment of PSC-derived Lung Tip-like Cells Into Immunocompetent Mice/ M. Herriges, Boston, MA 1015 64 Cu-PEG-FUD for Non-Invasive Detection of Murine-Induced Pulmonary Fibrosis/ K. Bernau, Madison, WI 1016 Noninvasive Quantification of Radiation Induced Lung Injury by Type 1 Collagen Probe- Translational Model With First in Human Study/ E.D. Abston, Boston, MA 1017 Fibroblast Activation Protein Inhibitor, a Promising Radiotracer in Fibrogenesis/ P. Lavis, Brussels, Belgium 1018 Novel Dual Action Peptide Therapeutic in Attenuation of Pulmonary Fibrosis/ D.C. Yang, Davis, CA 1019 Adipose Derived Stromal Cells-Induced Regulation of Micro RNA Modulates Telomere Length in Mouse Lung/ D. Anderson-Terhune, Phoenix, AZ 1020 Inhibiting a RNA Motif Binding Protein Attenuates Pulmonary Fibrosis in Mice/ R.H. Gomer, College Station, TX

BASIC • CLINICAL • TRANSLATIONAL RAPID: RAPID ABSTRACT POSTER DISCUSSION SESSION

C29

MORE THAN MEETS THE EYE: ADVANCED LUNG IMAGING

9:00 a.m. - 11:00 a.m.

Walter E. Washington Convention Center Room 103 A-B (Street Level)

Viewing

9:00-9:45 9:45-11:00

Summaries/Discussion

Chairing: S. Svenningsen, PhD, Hamilton, Canada J.C. Woods, PhD, ATSF, Cincinnati, OH E.A. Hermann, MD, MPH, New York, NY 201 Noninvasive Assessment of In Vivo Mouse Lung Microstructural Changes Due to Aging and PEEP/ M.L. Costa, Cincinnati, OH 202 Hyperpolarized 129 Xe Pulmonary Magnetic Resonance Imaging and Multiple Breath Washout Response to Elexacaftor-Tezacaftor-Ivacaftor in Adults With Cystic Fibrosis/ V.M. Diamond, Vancouver, Canada 203 Assessment of Lung Shrinking With Elastic Registration Technique on 3D-UTE Pulmonary MRI in Monitoring Idiopathic Pulmonary Fibrosis/ X. Yang, Beijing, China 204 New CT-based Metrics of Rib Cage Dynamics Between Inspiration and Expiration Reveal Accelerated Aging in COPD Among Smokers/ S.A. Nadeem, Iowa City, IA 205 Dictionary Learning to Predict COPD Progression Using Topological PRM/ S. Ram, Ann Arbor, MI 206 Effect of Contrast Viscosity on Pulmonary Blood Flow Measurement Using Dynamic Contrast-enhanced Computed Tomography/ Y. Xin, Boston, MA

ATS 2023 • Washington, DC