Final-Program-ATS-2023-AP.vp

TUESDAY • MAY 23

237

P630 Influenza A Infection in Aged Mice Is Associated With Impaired Viral Clearance and Dysregulated Immune Responses/ Y. Matsunaga, New Orleans, LA P631 The Role of Exosomal PD-L1 in Nontuberculous Mycobacterial Lung Disease: Association With Disease, Treatment Response and Immune Cell Survival/ C.-C. Shu, Taipei, Taiwan P632 Hepatitis C Viremia and Diffusing Capacity for Carbon Monoxide in Women With and Without Human Immunodeficiency Virus/ A. Curnow, San Francisco, CA P633 Identification of Small Molecules Targeting One of the P38alpha MAPK Substate-docking Domains With Endothelial-Barrier-Function-stabilizing and Immunomodulatory Activity/ J.D. Hasday, Baltimore, MD P634 The Effects of Extracellular Heme on Coronaviruses Induced Pulmonary Inflammatory Responses/ G. Qu, Gainesville, FL P635 Anti-CD20 Permits Secondary Lung Gene Transfer: Implications for Gene Therapy Approaches in Cystic Fibrosis/ R.D.E. Clark, New Orleans, LA P636 Dysglycemia Affects the Airway Microbiome in Cystic Fibrosis/ L. Brenner, Boston, MA P637 Cystic Fibrosis Transmembrane Conductance Regulator Triple Modulator Strongly Inhibits Phagocytosis by Primary Human Primary Lung Macrophages/ D. Aridgides, Lebanon, NH P638 Neutrophil Elastase-Dependent Cleavage Dysregulates LTA4H Aminopeptidase Activity/ X. Xu, Birmingham, AL P639 The Novel Orai1 Antagonist ELD607 Rescues the Hyperinflammatory Ca 2+ Signaling Seen in CF Neutrophils/ J. Wrennall, Chapel Hill, NC P640 The Impact of CFTR Modulator Triple Therapy on Type 2 Inflammatory Response in Patients With Cystic Fibrosis/ A.M. Mehta, Charlottesville, VA P641 Single Cell Transcriptional Characterization of the Upper Airway in a Murine Model of Cystic Fibrosis/ C.M. Bojanowski, New Orleans, LA P642 Th2-inflammation in the Sputum and Plasma of Cystic Fibrosis Patients/ I. Simpson-Shelton, San Diego, CA P643 Patient Derived Airway Epithelial Basal Cells Reveal an Age Related Response to Respiratory Syncytial Virus Infection/ P. Lerou, Boston, MA

P619 CD62L Expression in Peripheral Blood Eosinophils in Severe Asthma Patients Concerning the Clinical Outcome of Biological Therapy/ J. Novosad, Hradec Králové, Czech Republic P620 Efficacy and Safety of Mepolizumab as an Add-on Therapy in Chinese Patients With Severe Eosinophilic Asthma: A Randomized, Double-Blind, Parallel Group Phase 3 Study/ R. Chen, Guangzhou, China P621 Efficacy and Safety of Dupilumab in Patients With Persistent Asthma From the Asia-Pacific Region: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 3 Study/ Q. Zhang, Guangdong, China P622 Efficacy and Safety of Dupilumab in Patients From China With Persistent Asthma: A Subgroup Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 3 Study/ Q. Zhang, Guangdong, China

BASIC • TRANSLATIONAL THEMATIC POSTER SESSION

C32

THE AIRWAY BATTLE FOR DOMINANCE: IMMUNE SYSTEM VERSUS INFECTIONS

9:00 a.m. - 4:15 p.m.

Walter E. Washington Convention Center Area F, Hall C (Lower Level)

Viewing: Posters will be on display for entire session

11:30-1:15

Discussion: 11:30-12:15 authors will be present for individual discussion

12:15-1:15 authors will be present for discussionwith assigned facilitators.

P624 Effect of Influenza Immunization With Inactivated Trivalent Polymer-subunit Vaccine in Lung Transplant Recipients/ I. Revenco, Chisinau, Moldova, Republic of P625 Immunity Against Haemophilus Influenzae Type B Infection in Patients With Severe Bronchopulmonary Disorders Who Are on a Waiting List for a Lung Transplant, and Effects of Vaccination in This Patient Population/ I. Revenco, Chisinau, Moldova, Republic of P626 Novel iPS-derived MSCs Have Antibacterial Properties Against Pneumonia Relevant Pathogens/ J. Fandiño Gómez, Galway, Ireland P627 Lung Th17 TRM Cells Require CCR2 for Host Defense Against Pulmonary Klebsiella Infection/ T.P. Remcho, New Orleans, LA P628 TLR3 Signaling Is Required for Robust Extrafollicular B Cell Response (EF) in Influenza A/PR/8 Infection/ E.J. Keller, Davis, CA P629 Autoregulation of the Multifunctional IL-6 Family Cytokine Oncostatin M During Acute Bacterial Pneumonia/ Y. Lee, Boston, MA

ATS 2023 • Washington, DC

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