Final-Program-ATS-2023-AP.vp

TUESDAY • MAY 23

271

P407 Oxidative State of Protein Disulfide Isomerase Regulates Mitochondrial Induced Apoptosis in Cigarette Smoke Exposed Cells/ A. Blumental-Perry, Buffalo, NY P408 E-Cigarette Vaping Causes Mucociliary Dysfunction Through Impaired Autophagy/ C.M. Royer, Davis, CA P409 Secretion Proteome Profiling of Airway Epithelial Cultures Exposed to Burn Pit Smoke Condensates Reveals Combustion Type Specific Toxicity Patterns and Cellular Damage/ B. Reidel, Chapel Hill, NC P410 Inflammatory Profiling in Co-exposure of Ambient Particulate Matter (PM), Coronavirus Disease-2019 (COVID-19) and Lysophosphatidic Acid (LPA) a Ligand of the Receptor for Advanced Glycation End-product (RAGE)/ S. Podury, New York, NY P411 Defining Volatile Organic Compound Signatures of Airway Epithelial Cells After Environmental Exposures/ A. Linderholm, Davis, CA P412 Mimicking the Complex Phenotype of Chronic Obstructive Pulmonary Disease (COPD) in a Novel Pre-clinical Model: Combination of PPE, LPS and Poly IC in Mice/ E. Tantillo, Parma, Italy P413 Circadian Reprogramming in Chronic Airway Disease/ H. Mok, St. Louis, MO P414 Hypercapnia Induces Autophagy Arrest and Undermines Skeletal Myogenesis/ A. Jaitovich, Albany, NY P415 Lysophosphatidylcholine Acyltransferase 2 Promotes Cigarette Smoke Induced Emphysema Via Platelet-activating Factor/ H. Murano, Yamagata, Japan P416 Metabolomic Signatures in Mild COPD/ K. Wong, New York, NY P417 Intermittent Hypoxia Alters Tissue-specific Circadian Transcriptome in a Mouse Model of Obstructive Sleep Apnea/ B.S.C. Koritala, Cincinnati, OH P418 Type 1 Diabetes Accelerates Lung Damage in AAT Deficiency in Mice/ S.S. Park, Brooklyn, NY P419 Alpha-1 Antitrypsin Deficiency Accelerates Progression of Smoke Induced Emphysema in a Ferret Model/ S.S. Hussain, Birmingham, AL P420 Distinct Lung MicroRNA (miRNA) Signatures in

BASIC • TRANSLATIONAL THEMATIC POSTER SESSION

C70

COPD (AND LUNG CANCER) CLINICAL AND TRANSLATIONAL STUDIES

9:00 a.m. - 4:15 p.m.

Walter E. Washington Convention Center Area D, Hall C (Lower Level)

Viewing: Posters will be on display for entire session

11:30-1:15

Discussion: 11:30-12:15 authors will be present for individual discussion 12:15-1:15 authors will be present for discussionwith assigned facilitators. P423 Desert Particulate Matter From Afghanistan Increases Airway Obstruction in Human Distal Lungs Exposed to Type 2 Cytokine IL-13/ D.L. Cervantes, Denver, CO P424 The BODE Index and Epigenetic Age Are Associated With All-cause and Cause-specific Mortality Among U.S. Veterans With COPD/ E.S. Wan, Boston, MA P425 Association of Neutrophil Elastase-Rich Extracellular Vesicles With Lung and Systemic Inflammation in AATD Subjects/ V.P. Trelles, Gainesville, FL P426 COPD Subtyping Using Graphical Models on Clinical and Biomedical Data/ P.V. Benos, Gainesville, FL P427 Clinical Features of Genetic Resilience in COPD/ A.J. Ghosh, Syracuse, NY P428 Unsupervised Discovery of Gene Expression Networks Associated With Pulmonary Function, Emphysema, and Smoking in COPDGene/ I.R. Konigsberg, Aurora, CO P429 Identification of Altered Protein and MicroRNA Signatures in Extracellular Vesicle-enriched Fractions of Bronchoalveolar Lavage Fluid From Patients With Chronic Obstructive Pulmonary Disease/ M. Hylkema, Groningen, Netherlands P430 Expression Levels of MZB1 Reveal Two Distinct COPD Subtypes/ Y. Lai, Pittsburgh, PA P431 Embryologic Origins of Obstructive Lung Disease: Perinatal Nicotine Exposure Promotes Expression of Tissue Remodeling Genes in Lung/ J. Roman, Philadelphia, PA P432 Association of Clonal Hematopoiesis of Indeterminate Potential With Inflammatory Gene Expression in Patients With COPD/ S. Mansouri, Bad Nauheim, Germany P433 Association of Immune Checkpoint Inhibitor Treatment and Emphysema Progression in Patients With Urothelial Cancer/ S. Zo, Seoul, Korea, Republic of P434 ADAM-17 Concentration Is Increased in Severe Alpha-1-Antitrypsin Deficiency/ E. Leacy, Dublin, Ireland

Non-Small Cell Lung Cancer (NSCLC) and Chronic Obstructive Pulmonary Disease (COPD)/ R. Esposito, Caserta, Italy

ATS 2023 • Washington, DC