Final-Program-ATS-2023-AP.vp

TUESDAY • MAY 23

301

513 Crosstalk Between Memory B Cells and Fibroblasts Contributes to COPD Pathogenesis/ K.R. Bracke, Ghent, Belgium 514 Exhausted CD8+ T Cells Interacting With Myeloid and Non-immune Cells in the COPD Pathogenesis: Single-cell Analysis of Human Lung Tissue/ S. Shin, Seoul, Korea, Republic of 515 Apoptosis Inhibitor of Macrophage (AIM)/CD5l Is Involved in the Pathogenesis of Emphysema/ M. Takimoto-Sato, Sapporo, Japan 516 The Effect of HuR Depletion on Airway Obrstruction in COPD/ A.J. Dabo, Brooklyn, NY 517 The Effect of HuR Depletion in the Airway Epithelium in COPD/ A.J. Dabo, Brooklyn, NY 518 Macrophage Inflammatory and Metabolic Function Is Reduced With Loss of Adenine Nucleotide Translocase 1 (ANT1) in COPD/ J. Sui, Pittsburgh, PA 519 Proteomic Associations With Lung Function in COPDGene and SPIROMICS/ L. Ruvuna, Aurora, CO 520 Downregulation of MicroRNA-1, 133, and Let-7c Reduces to Control Prothymosin a Expression, A Novel Role in Chronic Obstructive Pulmonary Disease/ B. Su, Taipei, Taiwan C109 EVEN BETTER THAN THE REAL THING: ADVANCED MODELS OF LUNG DISEASE 2:15 p.m. - 4:15 p.m. Marriott Marquis Washington Marquis Ballroom, Salons 9-10 (Level M2) Poster Viewing 2:15-3:00 Discussion 3:00-4:15 Chairing: R. Krishnan, PhD, MS, Boston, MA R.L. Clifford, PhD, Nottingham, United Kingdom R.D. Britt, PhD, ATSF, Columbus, OH 1001 Building Epithelial Barrier in Whole-lung Tissue Engineering/ A.M. Greaney, Cambridge, MA 1002 Cell-specific Noxo1 Deletion in a Mouse Model of Cigarette Smoke-induced Emphysema and Pulmonary Hypertension/ S. Doswada, Giessen, Germany 1003 Using a Humanized Ventilator-on-a-chip to Investigate How Infectious Agents Alter Ventilation Induced Lung Injury/ S.N. Ghadiali, Columbus, OH BASIC • TRANSLATIONAL POSTER DISCUSSION SESSION

BASIC • TRANSLATIONAL POSTER DISCUSSION SESSION

C108 IMMUNITY AND INFLAMMATION IN COPD: NOVEL FINDINGS 2:15 p.m. - 4:15 p.m.

Walter E. Washington Convention Center Room 151 B (Street Level)

Poster Viewing

2:15-3:00 3:00-4:15

Discussion

Chairing: C.M. Freeman, PhD, Ann Arbor, MI

M.B. Fessler, MD, Research Triangle Park, NC A.O. Yildirim, PhD, Neuherberg, Germany 501 Profiling the Functional Microbiome in Mild COPD/ B. Isaacs, New York, NY 502 Integrative Analysis of Extracellular Lipocalin-2 and the Lung Microbiome in Smoking and COPD/ C. Healy, Dublin, Ireland 503 Chemical Activation of Protein Phosphatase 2A Slows Progression of Alpha-1 Antitrypsin Deficiency Associated Loss of Lung Function/ H. Ahmed, New York, NY 504 Role of LIM Kinase 1 in Driving Epithelial Plasticity in COPD/ C. Swaby, Baltimore, MD 505 Evaluating Novel Protein Phosphatase 2A Activators As Therapeutics for Cigarette Smoke Induced Loss of Lung Function/ B.A. Soto, Brooklyn, NY 506 Pulmonary Epithelial Gain-of-Function Toxicity in Alpha-1 Antitrypsin Deficiency/ K. Abo, Boston, MA 507 Morphometrics and Mucosal Immune Features in Lungs With End-stage Chronic Obstructive Pulmonary Disease/ C. De Fays, Brussels, Belgium 508 Lack of Fatty Acid Binding Protein 5 Prevents the Establishment of Resident Memory T Cells in the Lungs/ F.S. Gally, Denver, CO 509 Accumulation of PiZ Alpha-1 Antitrypsin Induces Pulmonary Toxicity/ X. Ma, New York, NY 510 Lipid Profiling Reveals Key Lipid Mediators in Cigarette Smoke-induced Experimental COPD/ S.F. Rehman, Sydney, Australia 511 A Baff-MYC Axis in the Vascular Niche Drives B Cell Recruitment and Proliferation in Severe Emphysema/ N. Mckenna, Houston, TX 512 Extracellular Vesicles From Patients With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease Induce the Synthesis of Proinflammatory Cytokines by Bronchial Epithelial Cells/ A. Celi, Pisa, Italy

ATS 2023 • Washington, DC