Final-Program-ATS-2023-AP.vp

WEDNESDAY • MAY 24

309

8:00 Single Cell RNAseq Redefines Vascular Cell Heterogeneity in the Lung N. Kaminski, MD, ATSF, New Haven, CT 8:15 Beyond RNA - Multi-Dimensional -Omics in the Pulmonary Circulation S.Y. Chan, MD, PhD, Pittsburgh, PA 8:30 Advancing the Understanding of the Immune Response and Inflammation in the Lung Through Omics C. Dela Cruz, MD, PhD, ATSF, New Haven, CT 8:45 PVDOMICs - Molecular-Based Phenotyping of Pulmonary Vascular Diseases A. Hemnes, MD, ATSF, Nashville, TN 9:00 From Omics to Targeted Treatment Options in BASIC • BEHAVIORAL • CLINICAL • TRANSLATIONAL SCIENTIFIC SYMPOSIUM CME Credits Available: 1.5 IT’S ABOUT TIME! THE CIRCADIAN CLOCK IN LUNG DISEASE, FROM BENCH TO BEDSIDE Assemblies on Respiratory Structure and Function; Allergy, Immunology and Inflammation; Environmental, Occupational and Population Health; Respiratory Cell and Molecular Biology; Sleep and Respiratory Neurobiology 8:00 AM - 9:30 AM Walter E. Washington Convention Center Room 150 A-B (Street Level) Target Audience Researchers interested in understanding the molecular mechanisms that involve the circadian clock in chronic lung diseases, physicians, physician-scientists, trainees, clinical fellows, junior-senior investigators, etc. Objectives At the conclusion of this session, the participant will be able to: • to learn on the newly and rapidly evolving paradigms about circadian clock regulation in innate immunity, sleep and pathogenesis of chronic lung diseases • to identify potential clock targets that can modulate cellular functions and molecular pathways essential for lung development and for the treatment and management of chronic inflammatory lung diseases • to identify novel biomarkers that supports circadian disruption causal-effect relationships in chronic lung diseases progression; Develop novel clock-based targeted therapies that can ameliorate pathophysiological phenotypes of chronic lung diseases D9 Pulmonary Vascular Disease M. Rabinovitch, MD, Stanford, CA 9:15 Panel Discussion

This exciting Scientific Symposium explores the role of the circadian clock in the development of chronic lung disease. This session is fully translational, providing a bench-to-bedside view of clock biology, basic mechanisms of circadian clock dysregulation in development of OSA, COPD, and IPF, and clinical translation drawing on results of chronotherapy trials in asthma, showing the role of environmental influences on circadian biology and learning from individuals with sleep disorders. We have assembled an impressive and diverse group of speakers from across the globe and this promises to be an exceptional session. Chairing: H. Durrington, PhD, MA, MBChB, Manchester, United Kingdom I.K. Sundar, BSc, MSc, PhD, Kansas City, KS N.N. Jarjour, MD, ATSF, CPE, Madison, WI M.P. Knauert, PhD, MD, New Haven, CT 8:00 Sleep and Circadian Rhythms: Considerations for Diagnosis, Monitoring and Treatment V. Revell, PhD, Guildford, United Kingdom 8:15 Impact of Intermittent Hypoxia on Circadian H. Durrington, PhD, MA, MBChB, Manchester, United Kingdom 8:45 Clock in the Lung: How Environmental Cues Tik Tok I. Rahman, PhD, ATSF, Rochester, NY 9:00 Tik Tok of Pulmonary Fibrosis Using in Vitro and In Vivo models I.K. Sundar, BSc, MSc, PhD, Kansas City, KS 9:15 Bringing Circadian Biology to Medicine J.B. Hogenesch, PhD, Cincinnati, OH This session and the International Conference are supported by an independent medical educational grant from AstraZeneca LP and Boehringer Ingelheim Pharmaceuticals, Inc.. All CME sessions have been planned and implemented in accordance with the Accreditation Criteria of the Accreditation Council for Continuing Medical Education (ACCME®) and are free of the control of ineligible companies (formerly commercial interests). Dysregulation of Gene Expression and Physiology D.F. Smith, MD, PhD, Cincinnati, OH 8:30 Asthma… It’s a Matter of Time!

BASIC • BEHAVIORAL • CLINICAL SCIENTIFIC SYMPOSIUM CME Credits Available: 1.5

D10 AN AGE-FRIENDLY FRAMEWORK FOR CARING FOR OLDER ADULTS WITH CHRONIC LUNG DISEASE Assemblies on Behavioral Science and Health Services Research; Pulmonary Rehabilitation 8:00 AM - 9:30 AM Walter E. Washington Convention Center Room 143 A-C (Street Level)

ATS 2023 • Washington, DC