Final-Program-ATS-2023-AP.vp

WEDNESDAY • MAY 24

311

Chairing: Lael Yonker, MD. MGH, Boston, MACharles Dela Cruz, MD, PhD, ATSF. Yale New Haven Hosp, New Haven, CT Tina V.. Hartert, MD, MPH, ATSF. Vanderbilt Univ Ctr for Asthma Research, Nashville, TN 8:00 Introduction Lael Yonker, MD. MGH, Boston, MA 8:05 Respiratory Viral Considerations During Surges B. Petros, Boston, MA 8:26 Effects of Respiratory Viruses on the Airway F. Rezaee, MD, Cleveland, OH 8:47 Persistent Viral Reservoirs Post Infection C.Rosas-Salazar, MD, MPH, ATSF, Nashville, TN 9:08 Immune Shaping and Impact on Adults T. Hartert, MD, MPH, ATSF, Nashville, TN

8:22 Adoptive T Cell Transfer and CAR T Cell Therapy for Lung Cancer S.M. Albelda, MD, Philadelphia, PA 8:39 Neoadjuvant Checkpoint Blockade for Lung Cancer Immunotherapy Susan Scott, MD, Baltimore, MD 8:56 Immune Escape and Contribution of Neutrophils to Immune Checkpoint Inhibitor Treatment Failures A.M. Houghton, MD, Seattle, WA 9:13 The Diagnosis and Management of Immune Checkpoint Inhibitor-Related Pneumonitis C.R. Sears, MD, ATSF, Indianapolis, IN This session and the International Conference are supported by an independent medical educational grant from Merck & Co. All CME sessions have been planned and implemented in accordance with the Accreditation Criteria of the Accreditation Council for Continuing Medical Education (ACCME®) and are free of the control of ineligible companies (formerly commercial interests).

BASIC • TRANSLATIONAL MINI SYMPOSIUM

CLINICAL SCIENTIFIC SYMPOSIUM CME Credits Available: 1.5

D13

INNATE AND ADAPTIVE IMMUNE MECHANISMS REGULATING LUNG DISEASE

8:00 a.m. - 10:00 a.m. Walter E. Washington Convention Center Ballroom A (Level 3) Chairing: C.M. Bojanowski, MD, MSCR, ATSF,, New Orleans, LA

D12

THE POST-COVID VIRAL SURGE: HOW DID VIRAL EXPOSURES, OR LACK THEREOF, INFLUENCE PEDIATRIC AND ADULT IMMUNITY?

S.M. Cloonan, PhD, Dublin, Ireland M. Cano, MD, PhD, Saint Louis, MO C. Bonham, MD, Charlottesville, VA

8:00 a.m. - 10:00 a.m.

Walter E. Washington Convention Center Center Room152 A-B

Oral Presentations: 8:00 Tissue-resident Memory and TEMRA CD8+ T Cells in the Lungs of Patients With Mild-moderate COPD/ A.B. Villaseñor-Altamirano, Boston, MA 8:12 Galanin-positive Macrophages Are Intimately Associated With the Pulmonary Vasculature During Late Embryogenesis/ T. Saito, Stanford, CA 8:24 Proximate Effects of Infant Lower Respiratory Tract Infections on Lung and Immune Dysfunction: Findings From the CHILD Study/ M.V. Medeleanu, Toronto, Canada 8:36 Neutrophil Efferocytosis Locks Alveolar Macrophages in a Pro-resolution Phenotype at the Cost of Bacterial Control/ J. Better, Giessen, Germany 8:48 Viral Infection and Age Determine the Production of B-cell Homing and Survival Factors in the Human Infant Airway Epithelium/ E. Chorvinsky, Washington, DC

Objectives At the conclusion of this session, the participant will be able to: • be able to apply new clinical research knowledge to clinical practice • learn new findings about key conditions in pulmonary, critical care and sleep • have new strategies to manage the care of common conditions in pulmonary, critical care, and sleep As cases and hospitalizations for COVID-19 waned over the winter, we experienced adramatic surge of other respiratory viruses, leaving us with the question: how has viral exposures, or lack thereof, influenced pediatric and adult immunity? This session will tackle topics related to viral considerations of surges; the role of airway epithelial cell barriers in viral infections; the impact of persistent viral reservoirs and the altered microbiome post COVID-19; and how the immune system may have been shaped by COVID-19 and how these impacts aging health.

ATS 2023 • Washington, DC