Final-Program-ATS-2023-AP.vp

SATURDAY • MAY 20

31

3:30 An Introduction to Microbiome Analytics for Integrative Microbiome Studies J.K. Narayana, BS, MS, Singapore 3:45 Consultation Session

and apply this knowledge when designing studies of the lung microbiome • apply a combination of basic science and multi-dimensional computational approaches for investigating microbial function and mechanisms of disease. Audience will be equipped to prioritize mechanistic approaches to the microbiota This course provides an up to date and accessible introduction to microbiome analyses for trainees and investigators. The course will introduce methodologies used to study the lung microbiome using culture-independent methods. During the session, participants will learn how to design, execute, analyze and interpret a lung microbiome study. Experiences will include didactic sessions, facilitated small-group discussions on designing and executing lung microbiome studies, and demonstrations on the use of statistical software to analyze microbiome data. Attendees will be provided with a set of microbiome data as well as annotated code for hands-on analysis. Chairing: A.A. Pragman, MD, PhD, Minneapolis, MN R.P. Dickson, MD, Ann Arbor, MI L.N. Segal, MD, New York, NY 8:00 An Introduction to Thinking About the Microbiome R.P. Dickson, MD, Ann Arbor, MI 8:45 Contaminomics M.J. Cox, BSc(Hons), PhD, London, United Kingdom 9:15 Integrating Microbiota Findings With Our Disease Models A.A. Pragman, MD, PhD, Minneapolis, MN 9:45 Break 10:15 Longitudinal Microbiome Studies D. Bogaert, MD, PhD, Edinburgh, United Kingdom 10:45 Studying Viruses and Fungi in Lung Microbiome Studies R.G. Collman, MD, Philadelphia, PA 11:15 Hands-On Microbiome Analysis - Part I C. Brown, BA, MS, Ann Arbor, MI 12:15 Lunch 1:15 Hands-On Microbiome Analysis - Part II C. Brown, BA, MS, Ann Arbor, MI 1:45 Microbial-Host Interactions L.N. Segal, MD, New York, NY 2:15 Metagenomics and Metatranscriptomics C. Langelier, MD, PhD, San Francisco, CA 2:45 Break 3:15 Introduction to Integrative, Therapeutic and Environmental Applications in Microbiome Studies S.H. Chotirmall, MD, PhD, Singapore

BASIC • TRANSLATIONAL POSTGRADUATE COURSE CME Credits Available: 6

PG12 MOLECULAR TARGETING IN COPD - FROM BASICS THROUGH MULTI-OMIC INTEGRATION TO NOVEL THERAPEUTICS R Pre-registration and additional fees required. Attendance is limited. Member: $440 In-Training Member: $255 LMIC Member: $310 LMIC In-Training Member: $180 Non-Member: $540 In-Training Non-Member: $380 R Registrants must bring a laptop to the course to view the course material. Assemblies on Respiratory Cell and Molecular Biology; Environmental, Occupational and Population Health; Respiratory Structure and Function 8:00 AM - 4:00 PM Marriott Marquis Washington Monument (Level M4) Target Audience Basic science researchers looking for novel druggable targets in COPD. Clinicians (clinician scientist) interested in novel approaches to At the conclusion of this session, the participant will be able to: • understand genetic susceptibililty, disease heterogeneity and pathological mechanisms underlying COPD • learn about novel molecular pathways currently being targeted for future therapeutics • learn and understand how to use current technologies to delineate novel targets for drug discovery COPD is the third leading cause of death worldwide but there are only limited symptomatic therapeutic options available with no causal treatment able to reverse or prevent the progression of COPD, revealing a high unmet medical need for novel therapeutics. To combat this problem a thorough understanding of the molecular mechanisms behind COPD are crucial for the development of new targets. Here we present leading avenues of investigation that will enhance the participants understanding of COPD patho-mechanisms and how the integration of cutting-edge technologies can help in our stride towards finding more efficient therapies. treat COPD. Objectives

ATS 2023 • Washington, DC