Final-Program-ATS-2023-AP.vp

WEDNESDAY • MAY 24

331

BASIC • CLINICAL • TRANSLATIONAL CLINICAL TOPICS IN PULMONARY MEDICINE CME Credits Available: 1.5

D82 REPURPOSING EXISTING MEDICATIONS FOR TREATMENT OF COPD Assemblies on Clinical Problems; Respiratory Cell and Molecular Biology 12:00 PM - 1:30 PM Marriott Marquis Washington Marquis Ballroom Salon 6 (Level M2) Target Audience Providers who care for patients with COPD and individuals interested in COPD research Objectives At the conclusion of this session, the participant will be able to: • describe findings from experimental and observational studies supporting the potential efficacy of angiotensin receptor blockers, metformin, and antiplatelet therapy in COPD • understand the reason for discrepancies between experimental/observational studies and clinical trial results in COPD • evaluate emerging research that investigates repurposing existing medications for the treatment of COPD Researchers have struggled to identify effective systemic pharmacologic therapies for COPD. Current COPD management consists of inhaled bronchodilators with few add on therapies for certain patient populations. Recently, researchers have focused on whether systemic medications commonly prescribed for non-respiratory indications may be effective in the treatment of COPD. In this session we discuss the scientific and clinical evidence for repurposing angiotensin receptor blockers (ARBs), metformin, and antiplatelet therapy as disease-modifying agents in COPD. We will also review the disconnect between murine models and human observational studies compared to clinical trial results for statins and beta-blockers. A panel discussion will follow. Chairing: I.M. Adcock, PhD, London, United Kingdom S. Christenson, MD, MS, San Francisco, CA M.T. Dransfield, MD, Birmingham, AL 12:09 Murine Models to Study ARB in Emphysema E.R. Neptune, MD, ATSF, Baltimore, MD 12:18 Current Evidence for ARBs and Angiotensin II Pathway in COPD V. Tejwani, MD, Cleveland, OH 12:27 Mechanisms of Metformin in COPD F. Polverino, MD, PhD, Houston, TX 2023 Parker B. Francis Speaker C.L. Pistenmaa, MD, MS, Boston, MA A. Fawzy, MD, MPH, Baltimore, MD 12:00 Introduction

Wednesday Afternoon, May 24

CLINICAL ADULT CLINICAL CORE CURRICULUM

CME Credits Available: 1.5 MOC Points Available: 1.5

CC6 PULMONARY CLINICAL CORE CURRICULUM Education Committee 12:00 p.m. - 1:30 p.m. Target Audience Clinicians who are engaged in maintenance of certification activities Objectives At the conclusion of this session, the participant will be able to: • describe updates in the diagnosis and management of mild, moderate, and severe asthma in 2023 • identify the local and global impact of one's environment on asthma management • describe best practices for asthma management in the pregnant and post-partum woman Chairing: G. Garrison, MD, Burlington, VT J. Cho, MD, Iowa City, IA 12:00 Asthma Where We Live and Work: The Impact of Environmental Change on Asthma Control N. Nassikas, MD, Cambridge, MA 12:25 Inequities in Asthma Care: Addressing Social Determinants of Health and Disparities in Asthma Management A.Rusk, MD, Rochester, MN 12:50 An ICS for Two: Treating Asthma in the Prenatal and Perinatal Settings E. Batchelor, MD, Med, Phoenix, AZ 1:15 Questions and Answers

ATS 2023 • Washington, DC