Final-Program-ATS-2023-AP.vp

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SUNDAY • MAY 21

2:15 A Patient's Perspective J. Torrence, Henderson, NV 2:20 Epidemiological Approaches to Investigating Treatment Effects and Unmet Need E. Henkle, PhD, MPH, Portland, OR 2:40 New Data for Airway Clearance and Mucoactive Approaches in Bronchiectasis A. Basavaraj, MD, FCCP, ATSF, New York, NY 3:00 The Role of Long Term Antibiotic Treatments in Bronchiectasis T.R. Aksamit, MD, Rochester, MN 3:20 Neutrophils, Eosinophils and Endotyping Bronchiectasis J.D. Chalmers, MD, PhD, Dundee, United Kingdom 3:40 Wrap Up and Panel Discussion S.H. Kasperbauer, MD, Denver, CO This session and the International Conference are supported by an independent medical educational grant from Insmed Incorporated. All CME sessions have been planned and implemented in accordance with the Accreditation Criteria of the Accreditation Council for Continuing Medical Education (ACCME®) and are free of the control of ineligible companies (formerly commercial interests). NEURO-IMMUNE INTERACTIONS IN LUNG DEVELOPMENT AND DISEASE Assemblies on Respiratory Structure and Function; Respiratory Cell and Molecular Biology; Sleep and Respiratory Neurobiology 2:15 PM - 3:45 PM Marriott Marquis Washington Marquis Ballroom Salon 6 (Level M2) Target Audience Those with clinical and/or research responsibilities Objectives At the conclusion of this session, the participant will be able to: • understand the anatomy and function of the airwayneural network in development and physiology • understand how the airway neuralnetwork is altered in chronic lung disease • integrate this knowledge to better understand how current and prospective pharmacological and nonpharmacologicaltreatments modifying the airway neural network, improve symptoms in patients with chronic lung disease The vagal nerve integrates afferent and efferent peripheral nerve fibers that control the functions of a large number of internal organs including BASIC • TRANSLATIONAL SCIENTIFIC SYMPOSIUM CME Credits Available: 1.5 A88

the respiratory tract. Chronic inflammation drives plasticity of those neurons, contributing to increased neuronal density in a variety of pathological conditions including asthma and chronic cough. In addition, evidence is building for a role of the nervous system in guiding immunological responses. In fact, neuro-immune interactions are recognized to play key roles in inflammation and remodeling in a variety of chronic lung diseases. As a consequence, there is a need to review current concepts surrounding neuronal development, neuroplasticity and neuro-immune interactions in chronic lung disease. Chairing: N. Jendzjowsky, PhD, Torrance, CA R. Gosens, PhD, Groningen, Netherlands 2:15 In Utero Development of the Pulmonary Nervous System X. Ai, PhD, Boston, MA 2:33 Dissection of Neuroimmune Control of Lung Function in

Animal Models of Disease X. Sun, PhD, San Diego, CA 2:51 Airway Neuroplasticity in Asthma M.G. Drake, MD, Portland, OR 3:09 Macrophage Derived Netrin in Fibrosis E. Herzog, MD, PhD, New Haven, CT 3:27 Targeted Lung Denervation for COPD

D.-J. Slebos, MD, PhD, Groningen, Netherlands

BEHAVIORAL • CLINICAL SCIENTIFIC SYMPOSIUM CME Credits Available: 1.5

A89 CAN ENVIRONMENTAL INTERVENTIONS CHANGE THE SOCIAL DETERMINANTS OF HEALTH? Assemblies on Environmental, Occupational and Population Health; Behavioral Science and Health Services Research; International Health Committee 2:15 PM - 3:45 PM Walter E. Washington Convention Center Room 147 A-B (Street Level) Target Audience Trainees, clinicians, researchers, allied health personnel Objectives At the conclusion of this session, the participant will be able to: • describe approaches to quantifying SDOH in the context of high income and low income settings • define how global factors such as climate change influences the relationship between household energy insecurity and SDOH • define new strategies for changing the SDOH through environmental interventions

ATS 2023 • Washington, DC