Final-Program-ATS-2023-AP.vp

SUNDAY • MAY 21

45

BASIC • BEHAVIORAL • CLINICAL • TRANSLATIONAL MINI SYMPOSIUM ASTHMA, THE NEXT FRONTIER: NEW DEVELOPMENTS IN PATHOPHYSIOLOGY AND TREATMENT Chairing: R.D. Britt, PhD, ATSF, Columbus, OH F.J. Rosser, MD, MPH, Pittsburgh, PA Oral Presentations: 9:00 Association of Prenatal Maternal and Infant Vitamin D Supplementation With Offspring Asthma Outcomes/ L. Ramirez, Boston, MA 9:12 Ontogeny of Lung Lavage Granulocyte Patterns in Children With Problematic Wheeze/Asthma Infected With Rhinovirus/ W.G. Teague, Charlottesville, VA 9:24 Association of Sphingolipid De-novo Synthesis With Airway Reactivity in Response to Magnesium Sulfate/ A.F. Heras Barros, New York, NY 9:36 Spatial Analysis of Housing Problems and Asthma Control Among Children With Asthma in an Urban Environment/ P. Kaviany, Washington, DC 9:48 Airway Epithelial Expression of CCL8, CXCL11, FLG2, and CXCL9 Is Associated With Violence-related Distress and Atopic Asthma in Youth/ M. Yue, Pittsburgh, PA 10:00 Violence Exposure and Maltreatment During Childhood and Asthma in Youth and Adults With Positive Biomarkers of T Helper 2-High Immunity/ K.M. Gaietto, Pittsburgh, PA 10:12 Characterization of Airway and Esophageal Inflammation in Children With Severe Uncontrolled Asthma/ J. Erkman, New York, NY 10:24 Effect of Early-life Household Exposure to Lipopolysaccharide on Childhood Asthma Is Modified by 17q12-q21 Genotype/ S. Saxena, Nashville, TN 10:36 A Randomised, Double-Blind, Parallel Group, Multicentre, Stratified Study Evaluating the Efficacy and Safety of Once-Daily Fluticasone Furoate/Vilanterol Compared With Once-Daily Fluticasone Furoate in the Treatment of Asthma in Participants Aged 5-17 Currently Uncontrolled on Inhaled Corticosteroids/ P. Bareille, Stevenage, United Kingdom A13 9:00 a.m. - 11:00 a.m. Walter E. Washington Convention Center Ballroom B (Level 3)

BASIC • TRANSLATIONAL MINI SYMPOSIUM

A14

THIS IS GETTING COMPLICATED: EPIGENETICS, -OMICS, AND CELL SIGNALING IN PULMONARY HYPERTENSION

9:00 a.m. - 11:00 a.m.

Walter E. Washington Convention Center Room 152 A-B (Street Level)

Chairing: Y.C.C. Lai, PhD, Indianapolis, IN L. Farkas, MD, Columbus, OH

J. Aman, MD, PhD, Amsterdam, Netherlands

Oral Presentations: 9:00 Pericytes Contribute to the Vascular Remodeling of Pulmonary Hypertension/ T. Klouda, Boston, MA 9:12 Osteoprotegerin Has Distinct Roles in Pulmonary Vascular and Cardiac Remodelling in a Mouse Model of Pulmonary Arterial Hypertension/ A. Lawrie, London, United Kingdom 9:24 C-Type Natriuretic Peptide Signalling Attenuates the Development of Pulmonary Hypertension and Right Ventricular Remodelling/ J.P. Dignam, London, United Kingdom 9:36 Multi-omic Profiling of the Pulmonary Arterial Endothelium Reveals Disturbed Cell Adhesion and Extracellular Matrix Reorganization in Chronic Thromboembolic Pulmonary Hypertension/ J. Aman, Amsterdam, Netherlands 9:48 Cell Type Specific Targeting of Microglial Activation in the Thoracic Spinal Cord as a Novel Therapeutic Strategy for Pulmonary Hypertension and Right Ventricular Failure/ A. Razee, Los Angeles, CA 10:00 Single-nucleus Transcriptome Profiling Identifies Phenotypic Shift in Capillary Endothelial Subpopulations in Pulmonary Arterial Hypertension/ J. Dai, Chicago, IL 10:12 Acute Pressure Overload in the Right Ventricle (RV) Changes the Tortuosity, Orientation, and Hemodynamics of the Microcirculation/ I. Essafri, Aurora, CO 10:24 Comprehensive Characterization of RV Function in Pulmonary Arterial Hypertension Model With Mitochondrial Dysfunction/ M. Niihori, Tucson, AZ 10:36 Single-cell Transcriptomics and Machine Learning

Featured Speaker: 10:48

A Breath of Fresh Air: Community Partnerships to Advance Pediatric Asthma Care/ M. Trivedi, Worcester, MA

Approach to Identify Novel Targets to Treat Right Ventricle Hypertrophy/ A.A. Dekan, Tucson, AZ

ATS 2023 • Washington, DC