Final-Program-ATS-2023-AP.vp

90

SUNDAY • MAY 21

P1006 Upregulation of MOXD1 Is Associated With Changes in the Expression of Copper Transporters ATP7a and Ctr1 in IPF Fibroblasts/ L. Rosas, Columbus, OH P1007 Increased IL-25 Expression in Idiopathic Pulmonary Fibrosis and Role in Fibroblast Proliferation and Activation/ A. Kanwal, Newcastle, Australia P1008 CXCL6 Upregulates COL1A1 and COL1A2 mRNAs in IPF Fibroblasts by a Post-transcriptional Mechanism/ H. Bahudhanapati, Pittsburgh, PA P1009 Bax Inhibitor-1 (BI-1) Is a Multifaceted Inhibitor of ER Stress Induced Apoptosis in IPF Derived Fibroblasts/ D.W. Moore, Manassas, VA P1010 March8 Is a Novel Regulator of Lung Myofibroblast Differentiation/ G. Qian, Tyler, TX P1011 Distinct Roles of Canonical and Non-canonical WNT Signaling on Myofibroblast Differentiation/ T. Liu, Ann Arbor, MI P1012 Zip Kinase Is Involved in Progression of Myofibroblast Differentiation of Human Pleural Mesothelial Cells/ Y. Choo, Tyler, TX P1013 Loss of cIAP1 Inhibits Mitochondrial Function in Fibroblasts and Diminishes Myofibroblast Differentiation/ J.C. Horowitz, Columbus, OH P1014 Deregulated Lactate Expression by the Alteration of LDHA and LDHB in IPF Fibroblasts Promotes Myofibroblast Differentiation/ R. Nho, Columbus, OH P1015 REV-ERB a Role in TGFß1-induced Fibroblast to Myofibroblast Differentiation in Human Lung Fibroblasts: Implications for the Pathogenesis of Pulmonary Fibrosis/ C. Prasad, Kansas City, KS P1016 Profibrotic Behavior of Lung Fibroblasts Derived From MMP8-MMP13 Double Knockout Mice Is Associated With a Delayed Fibrosis Resolution/ A. Garcia, Mexico City, Mexico P1017 Inhibition of the Epigenetic Regulator CBX5 Promotes Fibroblast Metabolic Reprograming and Attenuates Lung Fibrosis/ J. Hong, Boston, MA P1018 miR-133a Mediated Regulation of Transgelin Via TGF-beta/Smad3 Signaling Pathway in Pulmonary Fibrosis/ F. Muneesa M, Mangalore, India P1019 Characterising the Contribution of Casein Kinase 1 Delta (CK1 d ) in TGF-ß-induced Fibrogenesis/ S.S. Zhang, Parkville, Australia P1020 Anastellin, a Bioactive Fragment of Fibronectin, Is Increased in Idiopathic Pulmonary Fibrosis/ A.H. Hansen, Herlev, Denmark

P994 Low Vascular Endothelial Growth Factor Levels and Increasing Environmental Stiffness Potentiate Vascular Hyper-remodeling in Computational Model of Idiopathic Pulmonary Fibrosis/ J. Leonard-Duke, Charlottesville, VA P995 Transcriptomic Signatures of Lung Stretch/ P. Martín, Oviedo, Spain

BASIC • CLINICAL • TRANSLATIONAL THEMATIC POSTER SESSION

A66

DISSECTING THE MATRIX AND MESENCHYMAL CELLS IN FIBROSIS

9:00 a.m. - 4:15 p.m.

Walter E. Washington Convention Center Area J, Hall C (Lower Level)

Viewing: Posters will be on display for entire session

11:30-1:15

Discussion: 11:30-12:15 authors will be present for individual discussion 12:15-1:15 authors will be present for discussionwith assigned facilitators. P997 Matricellular Protein CCN3 as a Target to Promote Lung Endothelial Homeostasis and Repair in the Fibrotic Lung/ K.R. Betageri, Rochester, MN P998 Effects of Stiffness, Matrix, and Culture Conditions on the DNA Methylation Patterns of Normal and IPF Lung Fibroblasts/ A.M. Scruggs, Ann Arbor, MI P999 Transglutaminase Type II (TGM2) Secretion Contributes to Changes in Extracellular Matrix (ECM) in Idiopathic Pulmonary Fibrosis (IPF) In Vivo and Lung Fibroblast Ex Vivo/ A. Estrada-Bernal, Pittsburgh, PA P1000 Oxidative Stress Drives Cytokine Expression and Inhibits Contractility of IPF Fibroblasts in Fibrotic Tissue Hydrogels/ J. Fernandez Davila, Manassas, VA P1001 Identification and Characterization of Fibroblast Subpopulations Using Redox in Fibrosis/ P. Link, Rochester, MN P1002 Proteomic Analysis of Mitochondria of Healthy Pulmonary Fibroblasts and Fibrotics Fibroblasts Exposed to Hypoxia/ A. Aquino-Galvez, Ciudad de México, Mexico P1003 Tollip Deficiency Enhances the Transcriptomic Response of TGFß-treated Primary Mouse Lung Fibroblasts/ C. López-Martínez, Oviedo, Spain P1004 Histone Lactylation Contributes to Human Lung Myofibroblast Differentiation in Response to TGF-beta/ E. Reed, Chicago, IL P1005 Targeting Repressive Histone H3K27me3 Medicated Lung Fibroblast Activation/ J. Zhou, Birmingham, AL

ATS 2023 • Washington, DC