ATS 2024 Final Program

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119

MONDAY • MAY 20

availability remains uneven, and treatment disparities are common. This symposium will foster discussion on how to enhance collaboration, promote best practices, and improve the availability and equitable allocation of ECMO going forward, as we prepare for the next pandemic. 9:15 Introduction 9:20 State of the in Veno-Venous ECMO 9:35 Innovations on the Horizon: Future Trends in ECMO for Respiratory Failure 9:50 The Equitable Use of Extracorporeal Life Support in Respiratory Pandemics and Beyond 10:05 Who Knows Best? Controversies & Best Practices in Lung Protection 10:20 Preparing for the Next Pandemic: Building a System that Works for All 10:35 Roundtable Panel Discussion B5 ROBERT SENIOR MEMORIAL SYMPOSIUM - COPD AS AN ENDOTHELIAL DISORDER: ENDOTHELIAL INJURY LINKING LESIONS IN THE LUNGS AND OTHER ORGANS Assemblies on Respiratory Cell and Molecular Biology; Clinical Problems; Pulmonary Circulation; Respiratory Structure and Function 9:15 a.m. - 10:45 a.m. San Diego Convention Center Room 6A (Upper Level) Target Audience Basic and translational scientists and clinicians involved in COPD research and/or management Objectives At the conclusion of this session, the participant will be able to: • to learn the cellular and molecular mechanisms of endothelial dysfunction in COPD • to understand the relationship between endothelial dysfunction and systemic inflammation in COPD BASIC • CLINICAL • TRANSLATIONAL BASIC CORE

• to learn about the latest therapeutic interventions targeting the endothelium in COPD COPD patients develop varying degrees of emphysema, small and large airway disease, and various co-morbidities. It has not been clear whether these co-morbidities share common underlying pathogenic processes with the pulmonary lesions. Recently, cigarette smoke-induced endothelial injury has been linked to pulmonary lesions in COPD and systemic co-morbidities. Herein, we review the evidence linking endothelial injury to COPD, and the pathways underlying endothelial injury and the “vascular COPD phenotype.” 9:15 When Not All Is Lost: Reversal of Emphysema by Restoration of Pulmonary Endothelial Cells 9:30 Endothelial Injury Linking Lesions in the Lungs and Other Organs in COPD 9:45 Capillary Endothelial Cells: The Fuse or the Fuel of Persistent Alveolar Inflammation in Advanced COPD? 10:00 The Unusual Suspect: Lymphatic Vessels in COPD 10:15 Vascular Pruning in COPD: A Hard Nut to Crack 10:30 Targeting the Endothelium in COPD: Insights from Clinical Trials B6 INTEGRATING EVIDENCE FROM RANDOMIZED TRIALS AND OBSERVATIONAL COHORTS IN SLEEP DISORDERED BREATHING Assemblies on Sleep and Respiratory Neurobiology 9:15 a.m. - 10:45 a.m. Target Audience This symposium is aimed at clinicians, researchers, and clinicians who are interested in understanding the evidence-base underlying therapies for sleep-disordered breathing Objectives At the conclusion of this session, the participant will be able to: • review existing methods for approaching causal inference • review clinical evidence for SDB treatment’s impact on cardiovascular disease both from experimental and observational data Marriott Marquis San Diego Marina Pacific Ballroom 18-19 (Ground Floor, North Tower) CLINICAL SCIENTIFIC SYMPOSIUM

ATS 2024 Conference Program • San Diego, CA