ATS 2024 Final Program

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196

MONDAY • MAY 20

12:15 Incorporating Socio-behavioral Research into TB Clinical Trials to Improve Patient Experiences and Provider Perceptions 12:30 Tuberculosis Testing and Latent Tuberculosis Infection Treatment Practices Among Health Care Providers 12:45 Provider Outreach and Community Engagement Efforts to Reduce TB Health Disparities

SPIROMICS study results and progress of other studies will be included. 12:00 How Do Different Categories of "Pre-COPD" Fit Together? 12:15 Investigating the Origins of Early COPD in the SOURCE 12:30 Sex-Based Differences in the Right Ventricle (RV) in COPD in SPIROMICS HF 12:45 Implications of COVID-19 for COPD (C4R study in SPIROMICS) MD25 UPDATES ON LUNG HALLMARKS OF AGING 12:00 p.m. - 1:00 p.m. San Diego Convention Center Room 8 (Upper Level) Target Audience Clinicians, physiologists, molecular biologists, epidemiologists, and all points in between Objectives At the conclusion of this session, the participant will be able to: • update on hallmarks of lung aging • determine whether lung and pulmonary vasculature aging/cellular senescence is related to disease pathogenesis • describe new findings about other cellular perturbations and lung aging in chronic lung diseases Lung aging is associated with molecular and physiological changes that cause alterations in lung function, diminished pulmonary remodeling and regenerative capacity, and increased susceptibility to acute and chronic lung diseases. Recent findings show diverse mechanisms that support a role for several aging hallmarks including senescence, oxidative damage, telomeric maintenance failure, inflammation and metabolic dysfunction that contribute to lung aging. The purpose of this session is to have presentations on the state of scientific findingss on the molecular and cellular mechanisms of aging which contribute to the pathological features of lung aging and pulmonary dysfunction. 12:00 Cellular Hallmarks of Human Lung Aging - Lesson from Single Cell and 'Omics' Analyses NATIONAL INSTITUTE ON AGING MID-DAY SESSION

NHLBI, NIH MID-DAY SESSION MD24 NEWFINDINGS FROMTHE

SUBPOPULATIONS AND INTERMEDIATE OUTCOMES INCOPD STUDY (SPIROMICS ) FAMILYOF STUDIES: SPIROMICS, SOURCE, SPIROMICS HF Marriott Marquis San Diego Marina Pacific Ballroom 24-26 (Ground Floor, North Tower) Target Audience Researchers, medical trainees, those interested in origins and subtypes of COPD Objectives At the conclusion of this session, the participant will be able to: • understand “pre-COPD” as well as plans to investigate early COPD • understand associations between COPD and cardiovascular phenotypes • understand how the COVID-19 pandemic may have affected COPD patients SPIOMICS is a clinical observational study intended to identify different subpopulations of individuals w/COPD and ultimately define endotypes within this heterogeneous disease that are responsive to mechanism-specific interventions. SPIROMICS is performing intensive longitudinal phenotyping of a cohort that consists of individuals w/smoking history with and without COPD, and control participants without smoking history. SPIROMICS studies include: SOURCE, a cohort-design investigating COPD Origins; SPIROMICS Heart Failure, collecting cardiovascular measures in a subset of the SPIROMICS cohort; and C4R, a cohort of cohorts to determine factors that predict disease severity and long-term health impacts of COVID-19. Updates on 12:00 p.m. - 1:00 p.m.

ATS 2024 Conference Program • San Diego, CA