ATS 2024 Final Program

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SUNDAY • MAY 19

21

10:25 Biology of Lung Macrophage Subsets in Health and Disease

9:52 Airway Disorders and the Role of Sex as a Biological Variable 10:08 X Chromosome Associations with Chronic Obstructive Pulmonary Disease and Related Phenotypes 10:24 Role of Sex on Lung Function Trajectories After Preterm Birth: Links to COPD? 10:40 Session Wrap Up

BASIC • CLINICAL • TRANSLATIONAL SCIENTIFIC SYMPOSIUM

A6 ROLE OF SEX IN PULMONARY DISEASE ACROSS THE LIFESPAN Assemblies on Pediatrics; Respiratory Cell and Molecular Biology 9:15 a.m. - 10:45 a.m. San Diego Convention Center Room 24A-C (Upper Level) Target Audience Physicians, advanced practice providers, researchers Objectives At the conclusion of this session, the participant will be able to: • apply new knowledge in using translationally relevant experimental models and approaches to interrogate the role of sex chromosomes in lung diseases • describe the role of X- or Y-chromosomes in mediating lung disease pathophysiology • define the mechanisms by which sex modulates gene expression and distinct biological pathways leading to sex-specific susceptibility or resilience in lung diseases Sex-specific differences underlie the pathogenesis of many lung diseases. Sex hormones are often considered to underlie differences in susceptibility or resilience to disease. Mammalian cells show intrinsic sex-specific differences suggesting a role of sex chromosomes in differences in prevalence and susceptibility to lung diseases, particularly since genes on the X and Y chromosomes are differentially expressed between male and female cells because of X-chromosome inactivation, gene dosage, or genomic imprinting. The effect of sex chromosomes (X and Y) on the modulation of pulmonary diseases have been recently highlighted in pulmonary diseases ranging the lifespan. This symposium session will address knowledge gaps in the understanding of the contribution of sex to lung diseases across the lifespan. 9:15 Sex Chromosomes Mediate Sex-Specific Differences in Lung Diseases Across the Lifespans 9:20 Role of Sex Chromosomes in Neonatal Lung Injury 9:36 The Role of Y Chromosome in Pulmonary Hypertension

CLINICAL SCIENTIFIC SYMPOSIUM

A7 WE’RE REALLY COOKING NOW! PRO-CON DEBATE ON GAS STOVE RISKS TO LUNG HEALTH Assemblies on Environmental, Occupational and Population Health; Behavioral and Health Services Research; International Health Committee 9:15 a.m. - 10:45 a.m. Marriott Marquis San Diego Marina Pacific Ballroom 18-19 (Ground Floor, North Tower) Target Audience Providers of lung health and public health, crossing the majority of respiratory disease states. Particularly interesting to those focused on preventive care, occupational medicine, and air pollution. Objectives At the conclusion of this session, the participant will be able to: • describe the risks and benefits of cooking with liquified petroleum gas (LPG) in both resource rich and resource poor regions • better counsel patients on their personal risk of exposure if they use gas stoves and ways to mitigate the risk • describe health policy implications of promoting or limiting access to gas stoves Are gas stoves good, bad, or maybe both? In this session, debate will ensue to evaluate the harms and benefits of gas stove cooking in high and low income countries, and the implications of potential policy change to the cooking landscape. 9:15 Are Gas Stoves the Problem? A High-Income Country Pro-Con Debate; Pro: Gas Stoves Cause Lung Disease 9:27 Are Gas Stoves the Problem? Con: Just the Facts, Please

ATS 2024 Conference Program • San Diego, CA