ATS 2024 Final Program

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82

SUNDAY • MAYs 19

P490 Establishment of a Human In Vitro Model to Study Airway Epithelial Injury and Regeneration P491 Live Lung Imaging to Define the Cell Specificity of Alveolar Defense P492 Disease Modeling of Pulmonary Alveolar Microlithiasis Using Human Induced Pluripotent Stem Cells P493 Preclinical Murine Model for Airway Cell Transplantation P494 Stiffness Sensitizes Mouse Precision Cut Lung Slices to TGF-ß Induced Fibrogenesis: Benchmarking PF670462 Using Global Proteomics P495 The Creation of In-vitro Cellular Model for Interstitial Lung Disease P496 CRISPR/Cas9 Genome Editing Allows Generation of the Mouse Lung in a Rat P497 Emerging Volumetric Imaging Coupled to Multi-omics: Probing Cellular Dynamics and Tissue Niches of Human Lungs in Health and Disease P498 Molecular Imaging With Fibrogenesis-targeted Positron Emission Tomography Quantifiesdisease Activity in an Experimental Model of Pulmonary Fibrosis P499 Chip Cytometry for Simultaneous Measurement of Protein and MRNA Markers on Single Cell Level P500 Effective Pharmacological Modulation of Biomarkers in Lung Tissue of Pulmonary Fibrosis Patients Ex Vivo P501 Testing the Viability and Efficacy of Small Molecule Inhibitors in T-cells in Cryopreserved Precision Cut Lung Slices: New Insights for Long Term-storage Lung Organoids P502 Genetic Locus Associated With Bleomycin Induced Lung Fibrosis in Mice P503 Exhaustive Exercise Alters Exhaled Breath Volatile Organic Compounds: Insights From Elite Ultra-marathon Runners P504 Real-Time Confocal Imaging of Alveolar Barrier Recovery After Staphylococcal Lung Injury P505 Analysis of Alveolar Epithelial Regeneration in Two Acute Lung Injury Models Using Lineage Tracing

BASIC • TRANSLATIONAL THEMATIC POSTER SESSION

A71 CUTTING EDGE TECHNOLOGIES FOR LUNG DISCOVERY 9:15 a.m. - 4:15 p.m. San Diego Convention Center Area E (Hall A-B2, Ground Level) Viewing: Posters will be on display for entire session Discussion: 11:30-12:30 Discussionwith facilitators, authors, andattendees 12:30-1:15 Authorswill beby their posters for individual discussionwithattendees P478 Multiplexative Imaging Localizes Interstitial Macrophage Subsets Within Human Lung Structures P479 Secretion of Mesenchymal Stromal Cells-derived Exosomes Is Enhanced by Culturing on Lung Extracellular Matrix Hydrogels P480 The Development of Novel Tunable Polymeric Nanoparticles for Gene Therapies Directly into Pulmonary Capillary Endothelial Cells P481 Direct Lung Explant Culture Is an Efficacious Model for Testing Therapeutics in Primary SSc-ILD Tissue P482 Identification of Antifibrotic N23Ps’ Mode of Action (MoA) by Advanced 3D Human Fibrosis Models P483 Engineered Lung Microtissues to Model Macrophage Mechano-activation in Pulmonary Fibrosis and Anti-fibrosis Therapies P484 Determination of Surfactant Secretion in Precision-Cut Slices of Mouse Lung P485 Bleomycin Induces Senescence and Cell Death in Novel Induced-Usual Interstitial Pneumonia (iUIP) Mouse Precision-Cut Lung Slices P486 Ex Vivo Testing of Antifibrotic Drugs in a Long-term Culture of Precision-cut Lung Slices (PCLS) P487 Airway and Alveolar Organoids From Bronchoalveolar Lavage Fluid P488 A 3D Human Alveolar Model of Idiopathic Pulmonary Fibrosis to Understand Mechanisms That Initiate Fibrogenesis and Screen Therapeutics P489 Generation of a Mouse Model of Lung Fibrosis With Accumulation of Basal-like Cells

ATS 2024 Conference Program • San Diego, CA