ATS 2024 Final Program

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SUNDAY • MAY 19

83

P506 Human Induced Pluripotent Stem Cell-derived Lung Epithelial Cells in Micro-patterned Culture Distinguish SARS-COV-2 Variant Strains P507 Benchmarking of Single Cell RNA Sequencing Technologies: Evaluation of Cell Type Capture Efficiency in Human Lung Tissue and the Superiority of FRP in Conserving High Cellular Diversity P508 Impact of Expansion Medium on Progenitor Potential of Tracheospheres P509 The Successful Cryoconservation of Precision Cut Lung Slices (PLCS) Facilitates Translational Lung Research P510 Unraveling Invasion Modes: Extracellular Matrix Stiffness and Fibroblast Dynamics in 3D Lung Cancer Model P511 Generation of Fully Functional 2D and 3D Human Small Airway Models P512 Mirna Detection Using Particles in Exhaled Air (PExA): Development and Validation for Investigating Pulmonary Disorders P513 Developing Tissue Engineering Techniques for the Study of Crosstalk Between Healthy Cells and Fibrotic Extracellular Matrix in Idiopathic Pulmonary Fibrosis A72 EPITHELIAL CELLS: KEY CULPRITS IN PULMONARY FIBROSIS 9:15 a.m. - 4:15 p.m. San Diego Convention Center Area E (Hall A-B2, Ground Level) Viewing: Posters will be on display for entire session Discussion: 11:30-12:30 Discussionwith facilitators, authors, andattendees 12:30-1:15 Authorswill beby their posters for individual discussionwithattendees P515 Investigating the Impact of Sex Hormones on the Onset of Pulmonary Fibrosis Using Human Induced Pluripotent Stem Cell-derived Alveolar Epithelial Type 2 Cells BASIC • TRANSLATIONAL THEMATIC POSTER SESSION

P516 Movement of Epithelial Cells in Idiopathic Pulmonary Fibrosis (IPF) Is Associated With the Extent of Lung Fibrosis P517 Increased Susceptibility to Injury of Rat Alveolar Epithelial Cellsafter Exposure to Nanoparticles P518 MMP-24 Is a Novel Profibrotic Factor Produced by KRT5+/ TP63+ Lung Basal Cells P519 Alveolar Basal Cell Differentiation Is Associated With MMP7 Expression and Affected by Fibroblast-secreted Factors P520 Nuclear Factor E2-related Factor 1 (Nrf1) and ER-associated Degradation (ERAD) Coordinate the Proteasome Response to Surfactant Protein C Aggregates in Alveolar Epithelial Cells P521 Analysis of Functional Dynamics of Healthy Type 2 Alveolar Epithelial Cells as Progenitor Cells in Response to Type 1 Alveolar Epithelial Cell Specific Lung Injury P522 Idiopathic Pulmonary Fibrosis Alveolar Epithelial Type 2 Cells Are a Putative Cell of Origin for Basal-Like Cells in Distal Lung P523 Screening of Multiple Signaling Pathways Converting Alveolar Type 2 to Type 1 Cells Using Human Induced Pluripotent Stem Cells P524 Impaired DNA Damage Repair in Alveolar Type II Cells in Idiopathic Pulmonary Fibrosis P525 Stress Fibers Are Present in Aberrant Senecent Epithelial Cells in Idiopathic Pulmonary Fibrosis, and Inhibition of Their Formation Prevents Cell Senescence In Vitro P526 Long-term ATP Exposure During Differentiation Induces a Profibrotic Profile in Small Airway Epithelial Cells but Not Bronchial Epithelial Cells P527 Cellular Genomics of Bronchoalveolar Lavage Reveals Insight into Mechanisms of Human Pulmonary Fibrosis P528 The Inhibitory Mechanism of Erythrocyte Membrane Protein Band 4.1-like 3 on Transforming Growth Factor-ß-Induced Epithelial-Mesenchymal Transition

ATS 2024 Conference Program • San Diego, CA