ATS 2024 Final Program

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84

SUNDAY • MAYs 19

BASIC • TRANSLATIONAL THEMATIC POSTER SESSION

BASIC • TRANSLATIONAL THEMATIC POSTER SESSION

A73 GENOMICS AND EPIGENOMICS IN LUNG DISEASES 9:15 a.m. - 4:15 p.m. Viewing: Posters will be on display for entire session Discussion: 11:30-12:30 Discussionwith facilitators, authors, andattendees 12:30-1:15 Authorswill beby their posters for individual discussionwithattendees P530 Lnc RNA T-536 and RNA Binding Protein RBM25 Interactions in the Development of Pulmonary Arterial Hypertension P531 Long Non-coding RNA in IPF: Regulatory Players in Lung Fibrosis P532 A Novel Basal Cell Variant Committed to Honeycomb Cysts in IPF Across MUC5B Haplotypes P533 In Idiopathic Pulmonary Fibrosis (IPF), MUC5B Promoter Variant Rs35705950 Correlates With DNA Hypomethylation in the Gene Promoter Area P534 Impact of the IPF-associated Variant rs62025270 on Lung Epithelial Cells: Modulation of AKAP13 Expression and Its Implications P535 Single-cell RNA Sequencing Analysis Reveals Regulatory T Cell Activation and Cell-cell Interactions in Idiopathic Pulmonary Fibrosis Lungs P536 Imbalance of DNA Methyltransferases (DNMTS) and Ten-eleven Translocation (TET) Enzymes Contribute to the Altered DNA Methylation Profile of Fibrotic Lung Fibroblasts P537 Maintenance of DNA Methylation Patterns by UHRF1 and DNMT1 in Normal and IPF Lung Fibroblasts P538 Lncrna Norad Promotes Pulmonary Fibrosis by Interacting With HNRNPK to Regulate ITGBL1 P539 Digital Spatial Gene Expression Profiling of Fibrosing Interstitial Lung Diseases P540 Cross-species Transcriptome Comparison Revealed Shared Similarities Between Ferret Sustained Pulmonary Fibrosis Model and Human Idiopathic Pulmonary Fibrosis San Diego Convention Center Area E (Hall A-B2, Ground Level)

A74 MITOCHONDRIA AND METABOLISM IN LUNG HEALTH AND DISEASE 9:15 a.m. - 4:15 p.m. San Diego Convention Center Area E (Hall A-B2, Ground Level) Viewing: Posters will be on display for entire session Discussion: 11:30-12:30 Discussionwith facilitators, authors, andattendees 12:30-1:15 Authorswill beby their posters for individual discussionwithattendees P542 SGLT2 Inhibitor Attenuates Pulmonary Arterial Remodeling Through PPAR? Activation P543 Mitoneet and Its Regulation of Mitochondrial Metabolism in Pulmonary Hypertension P544 The Effect of Mitotempo Treatment on HIF-1 a Stabilization and Hypoxia-induced Pulmonary Hypertension in Mice P545 Cellular Communication by Abnormally High Lactate Enhances Myofibroblast Differentiation Via G Protein-Coupled Receptor 81 and Cyclic Adenosine Mono Phosphate Under Hypoxia P546 Metabolomics Analysis of Irradiated Human Lung Fibroblasts and Mouse Lung Tissue Suggests That Overaccumulation of Lactate in Fibrosis Originates From Alanine-derived Pyruvate Rather Than Glycolysis-derived Pyruvate P547 Elevated Cell-free Hemoglobin Disrupts Pulmonary Endothelial Function and Is Associated With Mitochondrial Dysfunction in Sepsis Patients P548 Parkin Deficiency Exacerbates PM-induced Injury by Enhancing Airway Epithelial Necroptosis P549 GM-CSF Is Required for Regulation of Mitochondrial Fusion, Fission, and Mitophagy in Macrophages P550 PERK-mediated Metabolic Reprogramming by Interaction of ATF4 and ATF3 on Ppargc1a Promoter in Pulmonary Fibrosis P551 Tetrandrine Inhibits Alveolar Epithelial Type 2 Cells Senescence Via Regulation of Mitophagy and Attenuates Pulmonary Fibrosis

ATS 2024 Conference Program • San Diego, CA